Cellular Microarray - Revision history

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2009-09-02T07:41:15Z

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	#REDIRECT [[Cellular microarray]]		#REDIRECT [[Cellular microarray]] {{R from other capitalisation}}

Skittleys: redirecting to proper capitalization

2009-08-26T04:44:27Z

redirecting to proper capitalization

← Previous revision		Revision as of 04:44, 26 August 2009
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			#REDIRECT [[Cellular microarray]]
	A '''cellular microarray''', is a [[laboratory]] tool that allows for the [[multiplex (assay)\|multiplex]] interrogation of living [[cell (biology)\|cells]] on the surface of a solid support. The support, sometimes called a "chip", is spotted with varying materials, such as [[antibodies]], [[proteins]], or [[lipids]], which can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in [[phenotype]], or detection of a response from the cell, such as a specific [[secretion\|secreted]] factor. An example of cellular microarrays are [[PMHC Cellular Microarrays]].

	Cellular microarrays were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at [[Stanford University Medical Center]].



	==References==

	Chen DS, Davis MM (2006) Molecular and functional analysis using live cell microarrays. Curr Opin Chem Biol 10:28-34

	Chen DS, Soen Y, Stuge TB, Lee PP, Weber JS, Brown PO, Davis MM (2005) Marked Differences in Human Melanoma Antigen-Specific T Cell Responsiveness after Vaccination Using a Functional Microarray. PLoS Med 2: 10: e265 (http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371%2Fjournal.pmed.0020265)

	Soen Y., Chen D. S., Kraft D. L., Davis M. M. and Brown P.O. (2003) Detection and characterization of cellular immune responses using peptide-MHC microarrays. PLoS Biol. 1: E65 (http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0000065)

	Chen DS, Davis MM (2005) Cellular immunotherapy: Antigen recognition is just the beginning. Springer Semin Immunopathol 27:119–127

	Chen DS, Soen Y, Davis MM, Brown PO (2004) Functional and molecular profiling of heterogeneous tumor samples using a novel cellular microarray. J Clin Oncol 22:9507 (http://meeting.jco.org/cgi/content/abstract/22/14_suppl/9507)

	Soen Y, Chen DS, Stuge TB, Weber JS, Lee PP, et al. (2004) A novel cellular microarray identifies functional deficiences in tumor-specific T cell responses. J Clin Oncol 22:2510

	[[Category: Biotechnology]]

SteveChervitzTrutane: Copyediting the lead. Page link to multiplex (assay).

2008-10-23T02:13:03Z

Copyediting the lead. Page link to multiplex (assay).

← Previous revision		Revision as of 02:13, 23 October 2008
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	'''~~Cellular~~ ~~microarrays~~''', ~~are~~ ~~biological~~ ~~chips~~ that ~~allow~~ interrogation of living [[cell (biology)\|cells]] on the surface of a solid support. The ~~chips~~, spotted with varying materials, such as [[antibodies]], [[proteins]], or [[lipids]], can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in [[phenotype]], or detection of a response from the cell, such as a specific secreted factor. An example of cellular microarrays are [[PMHC Cellular Microarrays]].		A '''cellular microarray''', is a [[laboratory]] tool that allows for the [[multiplex (assay)\|multiplex]] interrogation of living [[cell (biology)\|cells]] on the surface of a solid support. The support, sometimes called a "chip", is spotted with varying materials, such as [[antibodies]], [[proteins]], or [[lipids]], which can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in [[phenotype]], or detection of a response from the cell, such as a specific [[secretion\|secreted]] factor. An example of cellular microarrays are [[PMHC Cellular Microarrays]].

	Cellular microarrays were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at [[Stanford University Medical Center]].		Cellular microarrays were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at [[Stanford University Medical Center]].

Dschen5 at 06:29, 10 July 2007

2007-07-10T06:29:44Z

← Previous revision		Revision as of 06:29, 10 July 2007
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	Chen DS, Davis MM (2005) Cellular immunotherapy: Antigen recognition is just the beginning. Springer Semin Immunopathol 27:119–127		Chen DS, Davis MM (2005) Cellular immunotherapy: Antigen recognition is just the beginning. Springer Semin Immunopathol 27:119–127

	Chen DS, Soen Y, Davis MM, Brown PO (2004) Functional and molecular profiling of heterogeneous tumor samples using a novel cellular microarray. J Clin Oncol 22:9507		Chen DS, Soen Y, Davis MM, Brown PO (2004) Functional and molecular profiling of heterogeneous tumor samples using a novel cellular microarray. J Clin Oncol 22:9507 (http://meeting.jco.org/cgi/content/abstract/22/14_suppl/9507)

	Soen Y, Chen DS, Stuge TB, Weber JS, Lee PP, et al. (2004) A novel cellular microarray identifies functional deficiences in tumor-specific T cell responses. J Clin Oncol 22:2510		Soen Y, Chen DS, Stuge TB, Weber JS, Lee PP, et al. (2004) A novel cellular microarray identifies functional deficiences in tumor-specific T cell responses. J Clin Oncol 22:2510

Dschen5 at 06:28, 10 July 2007

2007-07-10T06:28:24Z

← Previous revision		Revision as of 06:28, 10 July 2007
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	Chen DS, Soen Y, Stuge TB, Lee PP, Weber JS, Brown PO, Davis MM (2005) Marked Differences in Human Melanoma Antigen-Specific T Cell Responsiveness after Vaccination Using a Functional Microarray. PLoS Med 2: 10: e265 (http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371%2Fjournal.pmed.0020265)		Chen DS, Soen Y, Stuge TB, Lee PP, Weber JS, Brown PO, Davis MM (2005) Marked Differences in Human Melanoma Antigen-Specific T Cell Responsiveness after Vaccination Using a Functional Microarray. PLoS Med 2: 10: e265 (http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371%2Fjournal.pmed.0020265)

	Soen Y., Chen D. S., Kraft D. L., Davis M. M. and Brown P.O. (2003) Detection and characterization of cellular immune responses using peptide-MHC microarrays. PLoS Biol. 1: E65		Soen Y., Chen D. S., Kraft D. L., Davis M. M. and Brown P.O. (2003) Detection and characterization of cellular immune responses using peptide-MHC microarrays. PLoS Biol. 1: E65 (http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0000065)

	Chen DS, Davis MM (2005) Cellular immunotherapy: Antigen recognition is just the beginning. Springer Semin Immunopathol 27:119–127		Chen DS, Davis MM (2005) Cellular immunotherapy: Antigen recognition is just the beginning. Springer Semin Immunopathol 27:119–127

Dschen5 at 06:25, 10 July 2007

2007-07-10T06:25:56Z

← Previous revision		Revision as of 06:25, 10 July 2007
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	Chen DS, Davis MM (2006) Molecular and functional analysis using live cell microarrays. Curr Opin Chem Biol 10:28-34		Chen DS, Davis MM (2006) Molecular and functional analysis using live cell microarrays. Curr Opin Chem Biol 10:28-34

	Chen DS, Soen Y, Stuge TB, Lee PP, Weber JS, Brown PO, Davis MM (2005) Marked Differences in Human Melanoma Antigen-Specific T Cell Responsiveness after Vaccination Using a Functional Microarray. PLoS Med 2: 10: e265		Chen DS, Soen Y, Stuge TB, Lee PP, Weber JS, Brown PO, Davis MM (2005) Marked Differences in Human Melanoma Antigen-Specific T Cell Responsiveness after Vaccination Using a Functional Microarray. PLoS Med 2: 10: e265 (http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371%2Fjournal.pmed.0020265)

	Soen Y., Chen D. S., Kraft D. L., Davis M. M. and Brown P.O. (2003) Detection and characterization of cellular immune responses using peptide-MHC microarrays. PLoS Biol. 1: E65		Soen Y., Chen D. S., Kraft D. L., Davis M. M. and Brown P.O. (2003) Detection and characterization of cellular immune responses using peptide-MHC microarrays. PLoS Biol. 1: E65

Dschen5 at 06:15, 10 July 2007

2007-07-10T06:15:28Z

← Previous revision		Revision as of 06:15, 10 July 2007
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	References:		==References==

	Chen DS, Davis MM (2006) Molecular and functional analysis using live cell microarrays. Curr Opin Chem Biol 10:28-34		Chen DS, Davis MM (2006) Molecular and functional analysis using live cell microarrays. Curr Opin Chem Biol 10:28-34

Dschen5 at 06:13, 10 July 2007

2007-07-10T06:13:14Z

← Previous revision		Revision as of 06:13, 10 July 2007
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	Cellular microarrays were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at [[Stanford University Medical Center]].		Cellular microarrays were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at [[Stanford University Medical Center]].



	References:		References:

Dschen5 at 06:11, 10 July 2007

2007-07-10T06:11:37Z

← Previous revision		Revision as of 06:11, 10 July 2007
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	'''Cellular microarrays''', are biological chips that allow interrogation of living [[cell (biology)\|cells]] on the surface of a solid support. The chips, spotted with varying materials, such as [[antibodies]], [[proteins]], or [[lipids]], can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in [[phenotype]], or detection of a response from the cell, such as a specific secreted factor. An example of a cellular ~~microarray~~ ~~is the~~ [[PMHC ~~cellular~~ ~~microarray~~]].		'''Cellular microarrays''', are biological chips that allow interrogation of living [[cell (biology)\|cells]] on the surface of a solid support. The chips, spotted with varying materials, such as [[antibodies]], [[proteins]], or [[lipids]], can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in [[phenotype]], or detection of a response from the cell, such as a specific secreted factor. An example of cellular microarrays are [[PMHC Cellular Microarrays]].

	Cellular microarrays were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at [[Stanford University Medical Center]].		Cellular microarrays were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at [[Stanford University Medical Center]].

Dschen5 at 06:10, 10 July 2007

2007-07-10T06:10:52Z

← Previous revision		Revision as of 06:10, 10 July 2007
Line 1:		Line 1:
	'''Cellular microarrays''', are biological chips that allow interrogation of living [[cell (biology)\|cells]] on the surface of a solid support. The chips, spotted with varying materials, such as [[antibodies]], [[proteins]], or [[lipids]], can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in [[phenotype]], or detection of a response from the cell, such as a specific secreted factor. An example of a cellular microarray is the [[~~pMHC~~ microarray]].		'''Cellular microarrays''', are biological chips that allow interrogation of living [[cell (biology)\|cells]] on the surface of a solid support. The chips, spotted with varying materials, such as [[antibodies]], [[proteins]], or [[lipids]], can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in [[phenotype]], or detection of a response from the cell, such as a specific secreted factor. An example of a cellular microarray is the [[PMHC cellular microarray]].

	Cellular microarrays were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at [[Stanford University Medical Center]].		Cellular microarrays were developed by Daniel Chen, Yoav Soen, Dan Kraft, Patrick Brown and Mark Davis at [[Stanford University Medical Center]].