Membrane vesicle trafficking: Difference between revisions

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Membrane vesicle trafficking in eukaryotic animal cells involves movement of important biochemical signal molecules from synthesis-and-packaging locations in Golgi to specific 'release' locations on the inside of the plasma membrane of the secretory cell, in the form of Golgi membrane-bound micro-sized vesicles, termed membrane vesicles (MVs). In this process, the 'packed' cellular products are released/secreted outside the cell across plasma membrane. However, vesicular membrane is retained and recycled by the secretory cells. This phenomenon has key role in synaptic neurotransmission, endocrine secretion, mucous secretion, granular-product secretion by neurophils,etc. The scientists behind this discovery were awarded Nobel prize for the year 2013 (see External Links).

In the prokaryotic gram-negative bacterial cells, membrane vesicle trafficking is mediated via bacterial outer membrane bounded nano-sized vesicles, called outer membrane vesicles (OMVs). In this case, however, the OMV membrane is secreted as well, alongwith OMV-contents to outside the secretion-active bacterium. This phenomenon has key role in host-pathogen interactions, endotoxic shock in patients, invasion and infection of animals/plants, inter-species bacterial competition, qourum sensing, etc.

See also

• Host-pathogen interface
• Exocytosis
• Vesicle (Biology and Chemistry)

External Links

Nobel Prize of year 2013 in Physiology and Medicine - press release http://www.nobelprize.org/nobel_prizes/medicine/laureates/2013/press.html

[[Category: Biological interactions