Felsenstein's tree-pruning algorithm
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In statistical genetics, Felsenstein's tree peeling algorithm, due to Joseph Felsenstein, is an algorithm for computing the likelihood of a coalescent tree from a set of genotypes.
In particular, Felsenstein's tree peeling algorithm provides a computationally feasible scheme for finding maximum likelihood estimates for evolutionary trees from nucleic acid sequence data. Further, it allows the hypotheses to be tested about whether evolutionary rates are constant (by using likelihood ratio tests, and it can also indications of the likely sizes of error in the estimated trees.
References
- Felsenstein, Joseph (1981). "Evolutionary trees from DNA sequences: a maximum likelihood approach". J Mol Evol. 17 (6): 368โ376. doi:10.1007/BF01734359. PMID 7288891.