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MBD4

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Template:PBB Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene.[1][2][3]

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Interactions

MBD4 has been shown to interact with MLH1[2] and FADD.[4]

References

  1. ^ Hendrich B, Bird A (Nov 1998). "Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins". Mol Cell Biol. 18 (11): 6538–47. PMC 109239. PMID 9774669.
  2. ^ a b Bellacosa A, Cicchillitti L, Schepis F, Riccio A, Yeung AT, Matsumoto Y, Golemis EA, Genuardi M, Neri G (May 1999). "MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1". Proc Natl Acad Sci U S A. 96 (7): 3969–74. doi:10.1073/pnas.96.7.3969. PMC 22404. PMID 10097147.{{cite journal}}: CS1 maint: multiple names: authors list (link) Cite error: The named reference "pmid10097147" was defined multiple times with different content (see the help page).
  3. ^ "Entrez Gene: MBD4 methyl-CpG binding domain protein 4".
  4. ^ Screaton, Robert A (Apr 2003). "Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: A potential link between genome surveillance and apoptosis". Proc. Natl. Acad. Sci. U.S.A. 100 (9). United States: 5211–6. doi:10.1073/pnas.0431215100. ISSN 0027-8424. PMC 154324. PMID 12702765. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)

5 Cunha, S., Lin, Y.C., Goossen, E.A., Devette, C.I., Albertella, M.R., Thomson, S., Mulvihill, M.J., and Welm, A.L. (2014). The RON Receptor Tyrosine Kinase Promotes Metastasis by Triggering MBD4-Dependent DNA Methylation Reprogramming. Cell reports 6, 141-154.

Further reading

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