SPIRE1
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Comment: This draft has a disambiguated title.If this draft is accepted, an entry will need to be added to the disambiguation page for the primary name. The disambiguation page for the primary name is Spire (disambiguation). Robert McClenon (talk) 23:45, 18 May 2021 (UTC)
SPIRE1 is a protein that interacts with actin monomers and actin nucleating formin proteins [1]. SPIRE1 was first identified in Drosophilia melanogaster[2]. SPIRE1 contains an N-terminal KIND domain which binds formins and four actin-binding WH2 domains which nucleate actin filaments [3] [4].
References
- ^ "SPIRE1 - Protein spire homolog 1 - Homo sapiens (Human) - SPIRE1 gene & protein". www.uniprot.org.
- ^ Manseau, L. J.; Schüpbach, T. (September 19, 1989). "cappuccino and spire: two unique maternal-effect loci required for both the anteroposterior and dorsoventral patterns of the Drosophila embryo". Genes & Development. 3 (9): 1437–1452. doi:10.1101/gad.3.9.1437. PMID 2514120 – via PubMed.
- ^ https://pubmed.ncbi.nlm.nih.gov/15674283/
- ^ https://www.pnas.org/content/108/29/11884