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Virgil Percec

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This is an old revision of this page, as edited by Biruitorul (talk | contribs) at 17:42, 26 May 2021 (Again, this is where we talk about Percec, not where we go on about his school — we have a separate article for that.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.
  • Comment: Subject is definitely notable as per his h-index, but the awards list should be trimmed to include major awards that can be referenced. The Awards and Achievements section should also be referenced, especially the sentence making claims about the subject "educateing over 300 PhD and postdoctoral students with more than 70 of them being in faculty positions." nearlyevil665 16:28, 24 May 2021 (UTC)

Virgil Percec
File:Percec Virgil 006-sq-1920x1920.jpg
Born (1946-12-08) December 8, 1946 (age 78)
Academic background
EducationPolytechnic University in Iasi
(BA, 1969; PhD, 1976)
Academic work
Institutions
WebsiteProfessor Virgil Percec

Virgil Percec (born December 8, 1946)[1] is a Romanian-American chemist and P. Roy Vagelos Chair and Professor of Chemistry at the University of Pennsylvania. Expert in organic, macromolecular and supramolecular chemistry including self-assembly, biological membrane mimics, complex chiral systems, and catalysis. Pioneered the fields of liquid crystals with complex architecture[2], supramolecular dendrimers, Janus dendrimers and glycodendrimers, organic Frank-Kasper phases and quasicrystals, supramolecular polymers, helical chirality, Ni-catalyzed cross-coupling and multiple living and self-interrupted polymerizations. Most of these concepts were inspired by Nature and biological principles.

Life

Early life

Percec was born in December 1946 in Siret, Romania. His father Traian was a schoolteacher and painter; his mother was named Virginia. Virgil attended Eudoxiu Hurmuzachi High School in Rădăuți.

Education

Percec received his BS in Organic and Macromolecular Chemistry at the Polytechnic University in Iasi in 1969 and his PhD in 1976 at the Institute of Macromolecular Chemistry in Iasi[3] where he had Cristofor Simionescu as a mentor. In 1981 he defected his native country and after short postdoctoral stays at the University of Freiburg in Germany (July 1981 with H. -J. Cantow) and University of Akron, US (August 1981 to March 1982 with J. P. Kennedy) he joined the Department of Macromolecular Science of Case Western Reserve University (CWRU) in Cleveland, US in March 1982 as an Assistant Professor. He was promoted to Associate Professor in 1984 and to Professor in 1986. In 1991 he became director of Materials Research Science and Engineering Centers (MRSEC) and in 1993, he was awarded the Leonard Case Jr. Chair at CWRU. In 1999 he moved to the University of Pennsylvania in Philadelphia as P. Roy Vagelos Chair and Professor of Chemistry. He has been repeatedly a Visiting Professor at the Universities of Freiburg, Ulm and at the Max Planck Institute for Polymer Research in Mainz (all in Germany) and at the Royal Institute of Technology in Stockholm, Sweden.

Personal Life

Percec and his wife, Simona have a daughter Ivona Percec.[4] She earned a double major in Molecular Biology and Medieval Art from Princeton University and received an MD/PhD from University of Pennsylvania where she joined the faculty and surgery department.

Research

Percec has made scientific contributions in diverse areas, including the discovery of all helical stereoisomers of polyphenylacetylene, their interconversion and intramolecular electrocyclization with applications in chiral separation, sensors, membranes, molecular machines[5], the discovery of liquid crystals based on conformational isomerism: polyethers, poly(vinyl ether)s, macrocyclics, covalent and supramolecular dendrimers[6][7][8] the discovery of self-assembling dendrons, dendrimers and dendronized polymers; and the creation of helical rod-like and spherical viruses mimics. He generated the first organic Frank-Kasper phases and quasicrystals.[8][9][10][11] He revealed double-helices disregarding chirality and deracemization in crystal state, designed the sequence-rearrangement concept to transform dynamic racemic (atactic) into homochiral (isotactic) supramolecular polymers[12] and demonstrated acceleration of self-assembly and disassembly by fluorine and fluorous phase.[7] His discovery of self-interrupted and self-accelerated iterative organic synthesis, polymerizations and living polymerizations produced the first monodisperse polymers by noniterative synthesis.[13] More recently, he uncovered biological membrane mimics from Janus dendrimers, glycodendrimers and ionizable dendrimers; determined they self-assemble into monodisperse artificial cell-like mimics, co-assemble with bacterial and human cells, and generate one component mRNA delivery systems for virus vaccines and drugs.[14] He is also known for the methodologies he developed for organic, macromolecular and supramolecular synthesis: replacement of Pd with Ni in cross-coupling reactions, the concepts of mixed-ligands and catalytic solvents, phase-transfer catalyzed living condensation polymerization, new mechanisms for living polymerization of acetylenes, single-electron-transfer mediated organic and polymerization reactions including living polymerizations.[15][16]

Awards and achievements

Percec is the author of more than 800 scientific articles, 20 books and special issues and listed as inventor of at least 80 patents. Percec presented over 1200 endowed, plenary and invited lectures. He has served as the Editor of Journal of Polymer Science: Part A: Polymer Chemistry, Advances in Polymer Science and Book Series “Liquid Crystals”. He serves on Editorial and Advisory Scientific Boards of 24 International Journals, and of the advisory boards of many Academic and Industrial Institutions. Percec is a member of foreign Academies, received US and international awards, organized numerous National and International Symposia including Gordon Conferences, and IUPAC meeting. He educated over 300 PhD and postdoctoral students with more than 70 of them being in faculty positions.[17]

Awards

References

  1. ^ "Professor Virgil Percec – Percec Research Laboratory". web.sas.upenn.edu.
  2. ^ https://www.sas.upenn.edu/sasalum/newsltr/fall05/SASMagFa05_webfinb.pdf
  3. ^ "Home - Institute of Macromolecular Chemistry "Petru Poni" Iasi". icmpp.ro.
  4. ^ "Ivona Percec, MD, PhD - Penn Medicine Cosmetic Services". www.pennmedicine.org.
  5. ^ Simionescu, C. I.; Percec, V.; Dumitrescu, Svetlana (May 24, 1977). "Polymerization of acetylenic derivatives. XXX. Isomers of polyphenylacetylene". Journal of Polymer Science: Polymer Chemistry Edition. 15 (10): 2497–2509. Bibcode:1977JPoSA..15.2497S. doi:10.1002/pol.1977.170151018 – via Wiley Online Library.
  6. ^ Hudson, S. D.; Jung, H.-T.; Percec, V.; Cho, W.-D.; Johansson, G.; Ungar, G.; Balagurusamy, V. S. K. (October 17, 1997). "Direct Visualization of Individual Cylindrical and Spherical Supramolecular Dendrimers". Science. 278 (5337): 449–452. Bibcode:1997Sci...278..449H. doi:10.1126/science.278.5337.449 – via science.sciencemag.org.
  7. ^ a b https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852099
  8. ^ a b Percec, V.; Ahn, C.-H.; Ungar, G.; Yeardley, D. J. P.; Möller, M.; Sheiko, S. S. (January 24, 1998). "Controlling polymer shape through the self-assembly of dendritic side-groups". Nature. 391 (6663): 161–164. Bibcode:1998Natur.391..161P. doi:10.1038/34384 – via www.nature.com.
  9. ^ Ungar, Goran; Liu, Yongsong; Zeng, Xiangbing; Percec, Virgil; Cho, Wook-Dong (February 21, 2003). "Giant Supramolecular Liquid Crystal Lattice". Science. 299 (5610): 1208–1211. Bibcode:2003Sci...299.1208U. doi:10.1126/science.1078849. PMID 12595686 – via science.sciencemag.org.
  10. ^ Zeng, Xiangbing; Ungar, Goran; Liu, Yongsong; Percec, Virgil; Dulcey, Andrés E.; Hobbs, Jamie K. (March 24, 2004). "Supramolecular dendritic liquid quasicrystals". Nature. 428 (6979): 157–160. doi:10.1038/nature02368. PMID 15014524 – via www.nature.com.
  11. ^ Percec, Virgil; Dulcey, Andrés E.; Balagurusamy, Venkatachalapathy S. K.; Miura, Yoshiko; Smidrkal, Jan; Peterca, Mihai; Nummelin, Sami; Edlund, Ulrica; Hudson, Steven D.; Heiney, Paul A.; Duan, Hu; Magonov, Sergei N.; Vinogradov, Sergei A. (August 24, 2004). "Self-assembly of amphiphilic dendritic dipeptides into helical pores". Nature. 430 (7001): 764–768. Bibcode:2004Natur.430..764P. doi:10.1038/nature02770. PMID 15306805 – via www.nature.com.
  12. ^ Percec, Virgil; Imam, Mohammad R.; Peterca, Mihai; Wilson, Daniela A.; Graf, Robert; Spiess, Hans W.; Balagurusamy, Venkatachalapathy S. K.; Heiney, Paul A. (March 23, 2009). "Self-Assembly of Dendronized Triphenylenes into Helical Pyramidal Columns and Chiral Spheres". Journal of the American Chemical Society. 131 (22): 7662–7677. doi:10.1021/ja8094944. PMID 19309145.
  13. ^ Holerca, Marian N.; Peterca, Mihai; Partridge, Benjamin E.; Xiao, Qi; Lligadas, Gerard; Monteiro, Michael J.; Percec, Virgil (August 20, 2020). "Monodisperse Macromolecules by Self-Interrupted Living Polymerization". Journal of the American Chemical Society. 142 (36): 15265–15270. doi:10.1021/jacs.0c07912. PMID 32815364.
  14. ^ Percec, Virgil; Wilson, Daniela A.; Leowanawat, Pawaret; Wilson, Christopher J.; Hughes, Andrew D.; Kaucher, Mark S.; Hammer, Daniel A.; Levine, Dalia H.; Kim, Anthony J.; Bates, Frank S.; Davis, Kevin P.; Lodge, Timothy P.; Klein, Michael L.; DeVane, Russell H.; Aqad, Emad; Rosen, Brad M.; Argintaru, Andreea O.; Sienkowska, Monika J.; Rissanen, Kari; Nummelin, Sami; Ropponen, Jarmo (May 21, 2010). "Self-Assembly of Janus Dendrimers into Uniform Dendrimersomes and Other Complex Architectures". Science. 328 (5981): 1009–1014. Bibcode:2010Sci...328.1009P. doi:10.1126/science.1185547. PMID 20489021 – via science.sciencemag.org.
  15. ^ Rosen, Brad M.; Quasdorf, Kyle W.; Wilson, Daniella A.; Zhang, Na; Resmerita, Ana-Maria; Garg, Neil K.; Percec, Virgil (March 9, 2011). "Nickel-Catalyzed Cross-Couplings Involving Carbon−Oxygen Bonds". Chemical Reviews. 111 (3): 1346–1416. doi:10.1021/cr100259t. PMC 3055945. PMID 21133429.
  16. ^ Percec, Virgil; Guliashvili, Tamaz; Ladislaw, Janine S.; Wistrand, Anna; Stjerndahl, Anna; Sienkowska, Monika J.; Monteiro, Michael J.; Sahoo, Sangrama (November 24, 2006). "Ultrafast Synthesis of Ultrahigh Molar Mass Polymers by Metal-Catalyzed Living Radical Polymerization of Acrylates, Methacrylates, and Vinyl Chloride Mediated by SET at 25 °C". Journal of the American Chemical Society. 128 (43): 14156–14165. doi:10.1021/ja065484z. PMID 17061900.
  17. ^ "Group Members – Percec Research Laboratory".
  18. ^ "Global Highly Cited Researchers 2018 List Reveals Influential Scientific Researchers and their Institutions".
  19. ^ "Faculty of Natural Sciences". in.bgu.ac.il.
  20. ^ "Chapter in Romania". American Chemical Society.
  21. ^ "Societatea de Chimie din ROMÂNIA". www.schr.ro.
  22. ^ https://cen.acs.org/sponsored-content/acs-kavli-lectures.html
  23. ^ "The Israel Chemical Society". ics-website.
  24. ^ "OFI - Österreichisches Forschungs- und Prüfinstitut". www.ofi.at.
  25. ^ "Home". Swiss Chemical Society.
  26. ^ "PTN | Polymer Technology Netherlands". www.ptn.nu. May 23, 2019.