BW247
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| This article, BW247, has recently been created via the Articles for creation process. Please check to see if the reviewer has accidentally left this template after accepting the draft and take appropriate action as necessary.
Reviewer tools: Inform author |
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| Identifiers | |
|---|---|
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| Chemical and physical data | |
| Formula | C16H17N |
| Molar mass | 223.319 g·mol−1 |
| 3D model (JSmol) | |
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BW-247 is an antidepressant.[1][2]
BW-247 is a secondary amine, closely related in structure to the tricyclic antidepressants, which inhibits NA uptake in aortic strips[3] and rat cerebral cortex slices.[4] Unlike the tricyclic antidepressants, it is reported not to possess anticholinergic activity.[5]
References
- ^ Castañer, J., Roberts, P. J. (1979). "BW-247". Drugs of the Future. 4 (2): 92. doi:10.1358/dof.1979.004.02.1002432.
- ^ Ankier, S. I. (1986). "Progress in Medicinal Chemistry". 4 Recent Progress in the Development of New Antidepressant Drugs. Vol. 23. Elsevier. pp. 121–185. doi:10.1016/S0079-6468(08)70342-4.
- ^ R.A. Maxwell, P.D. Keenan, E. Chaplin, B. Roth and S. Batimanglidj Eckhardt, J. Pharmacol. Exp. Ther., 166 (1969) 320.
- ^ A.I. Salama, J.R. Insalaco and R.A. Maxwell, J. Pharmacol. Exp. Ther., 178 (1971) 474.
- ^ J.W. Bridges, J.G. Dent and P. Johnson, Life Sci., 18 (1976) 97.