List of Billboard Hot 100 number ones of 1995
These are the Billboard magazine Hot 100 number one hits of 1995.
| Issue Date | Song | Artist |
| January 7 | On Bended Knee | Boyz II Men |
| January 14 | On Bended Knee | Boyz II Men |
| January 21 | On Bended Knee | Boyz II Men |
| January 28 | Creep | TLC |
| February 4 | Creep | TLC |
| February 11 | Creep | TLC |
| February 18 | Creep | TLC |
| February 25 | Take a Bow | Madonna |
| March 4 | Take a Bow | Madonna |
| March 11 | Take a Bow | Madonna |
| March 18 | Take a Bow | Madonna |
| March 25 | Take a Bow | Madonna |
| April 1 | Take a Bow | Madonna |
| April 8 | Take a Bow | Madonna |
| April 15 | This Is How We Do It | Montell Jordan |
| April 22 | This Is How We Do It | Montell Jordan |
| April 29 | This Is How We Do It | Montell Jordan |
| May 6 | This Is How We Do It | Montell Jordan |
| May 13 | This Is How We Do It | Montell Jordan |
| May 20 | This Is How We Do It | Montell Jordan |
| May 27 | This Is How We Do It | Montell Jordan |
| June 3 | Have You Ever Really Loved A Woman | Bryan Adams |
| June 10 | Have You Ever Really Loved A Woman | Bryan Adams |
| June 17 | Have You Ever Really Loved A Woman | Bryan Adams |
| June 24 | Have You Ever Really Loved A Woman | Bryan Adams |
| July 1 | Have You Ever Really Loved A Woman | Bryan Adams |
| July 8 | Waterfalls | TLC |
| July 15 | Waterfalls | TLC |
| July 22 | Waterfalls | TLC |
| July 29 | Waterfalls | TLC |
| August 5 | Waterfalls | TLC |
| August 12 | Waterfalls | TLC |
| August 19 | Waterfalls | TLC |
| August 26 | Kiss From a Rose | Seal |
| September 2 | You Are Not Alone | Michael Jackson |
| September 9 | Gangsta's Paradise | Coolio featuring L.V. |
| September 16 | Gangsta's Paradise | Coolio featuring L.V. |
| September 23 | Gangsta's Paradise | Coolio featuring L.V. |
| September 30 | Fantasy | Mariah Carey Featuring O.D.B. |
| October 7 | Fantasy | Mariah Carey Featuring O.D.B. |
| October 14 | Fantasy | Mariah Carey Featuring O.D.B. |
| October 21 | Fantasy | Mariah Carey Featuring O.D.B. |
| October 28 | Fantasy | Mariah Carey Featuring O.D.B. |
| November 4 | Fantasy | Mariah Carey Featuring O.D.B. |
| November 11 | Fantasy | Mariah Carey Featuring O.D.B |
| November 18 | Fantasy | Mariah Carey Featuring O.D.B |
| November 25 | Exhale (Shoop Shoop) | Whitney Houston |
| December 2 | One Sweet Day | Mariah Carey and Boyz II Men |
| December 9 | One Sweet Day | Mariah Carey and Boyz II Men |
| December 16 | One Sweet Day | Mariah Carey and Boyz II Men |
| December 23 | One Sweet Day | Mariah Carey and Boyz II Men |
| December 30 | One Sweet Day | Mariah Carey and Boyz II Men |