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Lysozyme

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Lysozyme 3D structure.

Lysozyme is an enzyme (EC 3.2.1.17), commonly referred to as the "body's own antibiotic". It is abundantly present in a number of secretions, such as tears.

This enzyme functions by attacking peptidoglycan by hydrolyzing the bond that connects N-acetylmuramic acid with carbon four of N-acetylglucosamine.

Lysozyme levels in the blood are ofted increased in sarcoidosis.

In some forms of hereditary amyloid, the cause is a mutation in the lysozyme gene, which leads to accumulated lysozyme in several tissues (Online Mendelian Inheritance in Man (OMIM): 105200.