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Immunohistochemistry

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Immunohistochemistry is the process of detection of antigens in tissue using antibodies. The antibodies can be polyclonal or monoclonal in origin, the monoclonal being more specific in nature. Immunohistochemistry is widely used for diagnosis of cancers. Specific markers are known for various cancers.

  • CEA : used for colon cancer
  • CD15,30 : used for hodgkin's disease
  • alpha-fetoprotein : for yolk sac tumors