Single particle extinction and scattering
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Single Particle Extinction and Scattering (SPES) is a technique in physics that is used to characterise micro and nanoparticles in suspension in a fluid through two independent parameters, the diameter and the effective refractive index.[1][2]
A laser generate a gaussian beam which focuses inside a flow cell. A particle who passes in the focal region generates an interference in the beam, which is collected with a sensor. Trough this signal it is possible to derive the real part and the immaginary part of the forward scattering field, from each single particle.
The technique was developed to measure aerosols in air[3] and particles in liquid.[4]
References
- ^ Sanvito, Tiziano; Bigini, Paolo; Cavanna, Maria V.; Fiordaliso, Fabio; Violatto, Martina B.; Talamini, Laura; Salmona, Mario; Milani, Paolo; Potenza, Marco A. C. (November 2017). "Single particle extinction and scattering optical method unveils in real time the influence of the blood components on polymeric nanoparticles". Nanomedicine: Nanotechnology, Biology, and Medicine. National Center for Biotechnology Information, U.S. National Library of Medicine. pp. 2597–2603. doi:10.1016/j.nano.2017.07.008. PMID 28756089. Retrieved 16 June 2019.
- ^ Dawson, K. A.; Milani, P.; Castagnola, V.; Boselli, L.; Cella, C.; Araújo, J. M. de; Monopoli, M.; Cai, Q.; Sanvito, T. (2017-02-23). "Detecting the shape of anisotropic gold nanoparticles in dispersion with single particle extinction and scattering". Nanoscale. United Kingdom: Royal Society of Chemistry. pp. 2778–2784. doi:10.1039/C6NR08977A. Retrieved 2019-06-16.
- ^ https://doi.org/10.1007/s11051-017-3995-3
- ^ Milani, P.; Lenardi, C.; Paroli, B.; Cella, C.; Argentiere, S.; Sanvito, T.; Potenza, M. a. C. (2015-12-15). "Single particle optical extinction and scattering allows real time quantitative characterization of drug payload and degradation of polymeric nanoparticles". Scientific Reports. Nature (journal). p. 18228. doi:10.1038/srep18228. Retrieved 2019-06-16.
| This article, Single particle extinction and scattering, has recently been created via the Articles for creation process. Please check to see if the reviewer has accidentally left this template after accepting the draft and take appropriate action as necessary.
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