Draft:AB-MDMSBA

AB-MDMSBA
Identifiers
	IUPAC name N-[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]-3-(dimethylsulfamoyl)-4-methylbenzamide;
PubChem CID	172872001;
Chemical and physical data
Formula	C15H23N3O4S
Molar mass	341.43 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=C(C=C(C=C1)C(=O)N[C@@H](C(C)C)C(=O)N)S(=O)(=O)N(C)C;
	InChI InChI=InChI=1S/C15H23N3O4S/c1-9(2)13(14(16)19)17-15(20)11-7-6-10(3)12(8-11)23(21,22)18(4)5/h6-9,13H,1-5H3,(H2,16,19)(H,17,20)/t13-/m0/s1; Key:KYNAATZHNRULED-ZDUSSCGKSA-N;

Submission declined on 13 June 2025 by Fade258 (talk).

Thank you for your submission, but the subject of this article already exists in Wikipedia. You can find it and improve it at AB-MDMSBA instead.

If you would like to continue working on the submission, click on the "Edit" tab at the top of the window.
If you have not resolved the issues listed above, your draft will be declined again and potentially deleted.
If you need extra help, please ask us a question at the AfC Help Desk or get live help from experienced editors.
Please do not remove reviewer comments or this notice until the submission is accepted.

Where to get help

If you need help editing or submitting your draft, please ask us a question at the AfC Help Desk or get live help from experienced editors. These venues are only for help with editing and the submission process, not to get reviews.
If you need feedback on your draft, or if the review is taking a lot of time, you can try asking for help on the talk page of a relevant WikiProject. Some WikiProjects are more active than others so a speedy reply is not guaranteed.

How to improve a draft

Wikipedia:Contributing to Wikipedia – a basic overview on how to edit Wikipedia.
Help:Wikitext – how to use the markup
Help:Referencing for beginners – how to include references
Wikipedia:Article development – how to develop your article
Wikipedia:Writing better articles – how to improve your article
Wikipedia:Verifiability – make sure your article includes reliable third-party sources

You can also browse Wikipedia:Featured articles and Wikipedia:Good articles to find examples of Wikipedia's best writing on topics similar to your proposed article.

Improving your odds of a speedy review

To improve your odds of a faster review, tag your draft with relevant WikiProject tags using the button below. This will let reviewers know a new draft has been submitted in their area of interest. For instance, if you wrote about a female astronomer, you would want to add the Biography, Astronomy, and Women scientists tags.

Add tags to your draft

Editor resources

Easy tools: Citation bot (help) | Advanced: Fix bare URLs

Declined by Fade258 3 days ago. Last edited by FrescoBot 4 seconds ago. Reviewer: Inform author.

Resubmit

Please note that if the issues are not fixed, the draft will be declined again.

Submission declined on 9 June 2025 by DoubleGrazing (talk).

This draft's references do not show that the subject qualifies for a Wikipedia article. In summary, the draft needs multiple published sources that are:

in-depth (not just passing mentions about the subject)
reliable
secondary
independent of the subject

Make sure you add references that meet these criteria before resubmitting. Learn about mistakes to avoid when addressing this issue. If no additional references exist, the subject is not suitable for Wikipedia.

Declined by DoubleGrazing 8 days ago.

Comment: There is already an article on this topic. Fade258 (talk) 14:49, 13 June 2025 (UTC)

Comment: In accordance with Wikipedia's Conflict of interest policy, I disclose that I have a conflict of interest regarding the subject of this article. BCanalyst (talk) 07:25, 9 June 2025 (UTC)

AB-MDMSBA is a novel synthetic compound that has been sold as a designer drug. It has been detected by drug checking services in Australia and New Zealand being misrepresented as a benzodiazepine.^[1]^[2]

It is structurally similar to other arylsulfonamide-based synthetic cannabinoids such as QMPSB.^[3] This class of synthetic cannabinoid has previously been targeted toward greater selectivity of the cannabinoid receptor CB₂ over CB₁.^[4] The activity of AB-MDMSBA against either cannabinoid receptor is unknown.

References

^ "Synthetic cannabinoid AB-MDMSBA found in 'benzodiazepine' samples - The Know". theknow.org.au. 2024-12-10. Retrieved 2025-06-10.
^ "New synthetic cannabinoid misrepresented as a benzodiazepine". High Alert. Retrieved 2025-06-10.
^ Lebon F, Christophe B, Burton M, De Ryck M, Quéré L, Lambeng N (January 2007). "Arylsulfonamides as a new class of cannabinoid CB1 receptor ligands: Identification of a lead and initial SAR studies". Bioorganic & Medicinal Chemistry Letters. 17 (1): 272–277. doi:10.1016/j.bmcl.2006.09.049. PMID 17027269.
^ Ajello CW, Worm K, Bourdonnec BL, Savolainen MA, O'Hare H, Cassel JA, et al. (January 2009). "CB2 selective sulfamoyl benzamides: Optimization of the amide functionality". Bioorganic & Medicinal Chemistry Letters. 19 (2): 309–313. doi:10.1016/j.bmcl.2008.11.091. PMID 19091565.

[1] "Synthetic cannabinoid AB-MDMSBA found in 'benzodiazepine' samples - The Know". theknow.org.au. 2024-12-10. Retrieved 2025-06-10.

[2] "New synthetic cannabinoid misrepresented as a benzodiazepine". High Alert. Retrieved 2025-06-10.

[3] Lebon F, Christophe B, Burton M, De Ryck M, Quéré L, Lambeng N (January 2007). "Arylsulfonamides as a new class of cannabinoid CB1 receptor ligands: Identification of a lead and initial SAR studies". Bioorganic & Medicinal Chemistry Letters. 17 (1): 272–277. doi:10.1016/j.bmcl.2006.09.049. PMID 17027269.

[4] Ajello CW, Worm K, Bourdonnec BL, Savolainen MA, O'Hare H, Cassel JA, et al. (January 2009). "CB2 selective sulfamoyl benzamides: Optimization of the amide functionality". Bioorganic & Medicinal Chemistry Letters. 19 (2): 309–313. doi:10.1016/j.bmcl.2008.11.091. PMID 19091565.

[1]

[2]

[3]

[4]