Draft:Robert Howard (psychiatrist): Difference between revisions
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| Submission declined on 23 June 2025 by JacobTheRox (talk). The content of this submission includes material that does not meet Wikipedia's minimum standard for inline citations. Please cite your sources using footnotes. For instructions on how to do this, please see Referencing for beginners. Thank you.
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Comment: This biography of a living person has insufficient inline citations - only the 'Early life and education' and 'Selected publications' sections have inline citations. Moreover, some claims made in the 'Early life and education' such as him being born in Windsor are not verified by the source you have given. JacobTheRox(talk | contributions) 11:24, 23 June 2025 (UTC)
Robert Howard FRCPsych | |
|---|---|
| Born | March 29, 1961 |
| Nationality | British |
| Alma mater | University of Cambridge St Bartholomew’s Hospital Medical College |
| Known for | VLOSLP consensus criteria; clinical trials CALM-AD, DOMINO, ATLAS, ATTILA, PATHFINDER & ANTLER 75+ |
| Spouse | Nesa Howard |
| Children | 2 |
| Awards | Lifetime Achievement Award, Royal College of Psychiatrists (2019) |
| Scientific career | |
| Fields | Old-age psychiatry |
| Institutions | University College London North London Mental Health Partnership |
Robert Howard (born 1961) is a British psychiatrist and professor of old-age psychiatry. He is Professor of Old Age Psychiatry at University College London (UCL) and an Honorary Consultant with the North London Mental Health Partnership.[1] He co-defined the diagnostic criteria for very-late-onset schizophrenia-like psychosis (VLOSLP)[2] and has led several influential clinical trials shaping dementia and psychosis care.[3][4]
Early life and education
[edit]Howard studied medicine at the University of Cambridge, completed clinical training at St Bartholomew’s Hospital Medical College,[1] and entered psychiatric training at the Maudsley Hospital/Institute of Psychiatry under mentors Raymond Levy, Klaus Bergmann and Tony David.[5][failed verification]
Career
[edit]Howard worked as an academic psychiatrist from the 1990s at King’s College London and then became Professor of Old Age Psychiatry and Psychopathology from 2002 - 2014. Since 2015 he has been Professor of Old Age Psychiatry at UCL. From 2008 – 2011 he served as Dean of Royal College of Psychiatrists. [1][5][6][7]
Research
[edit]Howard has conducted many studies in old-age psychiatry, especially dementia and late-onset psychosis and depression.
As of 2025, he has published over 500 peer-reviewed articles, with an h-index of 105, and has led multiple landmark randomized controlled trials (RCTs) that shaped UK dementia and psychosis care policy.[8]
His most influential RCTs are summarised in the table below.
| Trial | Focus | Key findings | Year | Reference |
|---|---|---|---|---|
| CALM-AD | Donepezil for agitation in Alzheimer’s disease | Donepezil was not superior to placebo on the CMAI; no benefit detected | 2007 | [9] |
| DOMINO | Donepezil ± memantine in moderate–severe Alzheimer’s disease | Continued treatment sustained cognitive & functional benefit | 2012 | [3] |
| ATLAS | Low-dose amisulpride for VLOSLP | Significant symptom reduction; good tolerability | 2018 | [4] |
| MADE | Minocycline for mild Alzheimer’s disease | No benefit detected at either 200 mg or 400 mg dose; minocycline not recommended | 2020 | [10] |
| ATTILA | Telecare & assistive tech in dementia | Did not delay institutionalisation | 2021 | [11] |
| PATHFINDER | Problem Adaptation Therapy for depression in Alzheimer's disease | No sustained benefit at 6 months | 2024 | [12] |
| ANTLER 75+ (ongoing) | Antidepressant continuation vs discontinuation (≥ 75 years) | Multicentre RCT; results due 2027 | 2024– | [13] |
Howard also has supervised or mentored clinical researchers. Their research has spanned diverse areas of psychiatry and neuroscience, including pharmacology, neuroimaging, epidemiology, neuropathology, cognitive neuroscience, biomarkers, and the use of technology in mental health care. These include Suzanne Reeves, [14] Rebecca L. Gould, [15] Nigel J. Blackwood, [16] Derek K. Jones, [17] Jonathan D. Huntley, [18] Kathy Y. Liu, [19] Jean Stafford, [20] Harry Costello, [21] Jemma Hazan,[22] and Yuto Satake.[23]
Personal life
[edit]Howard lives in London and has a Jack Russell terrier named Layla.[24]
Selected publications
[edit]- Howard R et al. (2000). “Late-Onset Schizophrenia and Very-Late-Onset Schizophrenia-Like Psychosis: An International Consensus” Am J Psychiatry.[2]
- Howard R et al. (2007). “Donepezil for the Treatment of Agitation in Alzheimer's Disease” N Engl J Med.[9]
- Howard R et al. (2012). “Donepezil and Memantine for Moderate-to-Severe Alzheimer’s Disease” N Engl J Med. [3]
- Howard R et al. (2018). “Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS): a randomised, controlled, double-blind trial” Lancet Psychiatry.[4]
- Howard R et al. (2024). “Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial” Lancet Psychiatry.[12]
Books
[edit]- Presumed Curable: An Illustrated Casebook of Victorian Psychiatric Patients in Bethlem Hospital (with Colin Gale, 2003)[25]
Media
[edit]- Channel 4 documentary series "Bedlam" (2013)[26]
- BBC "Who Do You Think You Are?" (2019)[27]
- BBC One "Breakfast" (2025) [28]
Honours
[edit]- Trustee, Bethlem Museum of the Mind (since 2013)[29]
- Lifetime Achievement Award in Older People's Mental Health, Faculty of Old Age Psychiatry, Royal College of Psychiatrists (2019)[30]
References
[edit]- ^ a b c "Professor Rob Howard – UCL Profile". University College London. Retrieved 14 June 2025.
- ^ a b Howard, Robert (2000). "Late-onset schizophrenia and very-late-onset schizophrenia-like psychosis: an international consensus". American Journal of Psychiatry. 157 (2): 172–178. doi:10.1176/appi.ajp.157.2.172. PMID 10671383.
- ^ a b c Howard, Robert (2012). "Donepezil and Memantine for Moderate-to-Severe Alzheimer's Disease". New England Journal of Medicine. 366 (10): 893–903. doi:10.1056/NEJMoa1106668. PMID 22397651.
- ^ a b c Howard, Robert (2018). "Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS): a randomised, controlled, double-blind trial". The Lancet Psychiatry. 5 (8): 633–643. doi:10.1016/S2215-0366(18)30141-X. PMC 6015223. PMID 29880238.
- ^ a b Fannon, Dominic (2009). "E-interview: Robert Howard". Psychiatric Bulletin. 33 (8): 320–322. doi:10.1192/pb.bp.109.026799.
- ^ "Robert Howard – King's College London". King's College London. Retrieved 14 June 2025.
- ^ "Royal College of Psychiatrists Annual Review 2009" (PDF). Retrieved 14 June 2025.
- ^ "Robert Howard – Google Scholar". Retrieved 14 June 2025.
- ^ a b Howard, Robert J. (2007). "Donepezil for the treatment of agitation in Alzheimer's disease". The New England Journal of Medicine. 357 (15): 1382–1392. doi:10.1056/NEJMoa066583. PMID 17914039.
- ^ Howard, Robert (2020). "Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial". JAMA Neurology. 77 (2): 164–174. doi:10.1001/jamaneurol.2019.3762. PMID 31825415.
- ^ Gathercole, Rebecca (2021). "Assistive technology and telecare to maintain independent living at home for people with dementia: the ATTILA RCT". Health Technology Assessment. 25 (19): 1–208. doi:10.3310/hta25190. PMC 8020444. PMID 33755548.
- ^ a b Howard, Robert (2024). "Adapted Problem Adaptation Therapy for depression in mild-to-moderate Alzheimer's disease (PATHFINDER)". Alzheimer's & Dementia. 20 (4): 2990–2999. doi:10.1002/alz.13766. PMC 11032547. PMID 38477423.
- ^ "Antidepressants to prevent relapse in depression in older people (ANTLER 75+ Trial)". ISRCTN Registry. Retrieved 13 June 2025.
- ^ Reeves, Suzanne (2017). "Therapeutic window of dopamine D2/3 receptor occupancy to treat psychosis in Alzheimer's disease". Brain. 140 (4): 1117–1127. doi:10.1093/brain/awx043. PMID 28334844.
- ^ Gould, Rebecca L. (2006). "Brain mechanisms of successful compensation during learning in Alzheimer disease". Neurology. 67 (6): 1011–1017. doi:10.1212/01.wnl.0000237391.72386.aa. PMID 17000961.
- ^ Blackwood, Nigel J. (2004). "Persecutory delusions and the determination of self-relevance: an fMRI investigation". Psychological Medicine. 34 (4): 591–596. doi:10.1017/S0033291703008997. PMID 15099414.
- ^ Jones, Derek K. (2005). "The effect of filter size on VBM analyses of DT-MRI data". NeuroImage. 26 (2): 546–554. doi:10.1016/j.neuroimage.2005.02.013. PMID 15907378.
- ^ Huntley, Jonathan D. (2017). "Adaptive working memory strategy training in early Alzheimer's disease: randomised controlled trial". The British Journal of Psychiatry. 210 (1): 61–66. doi:10.1192/bjp.bp.116.185108. PMID 27682595.
- ^ Liu, Kathy Y. (2020). "Neuropsychiatric symptoms in limbic-predominant age-related TDP-43 encephalopathy and Alzheimer's disease". Brain. 143 (12): 3842–3849. doi:10.1093/brain/awaa333. PMID 33169114.
- ^ Stafford, Jean (2021). "Association between risk of dementia and very late-onset schizophrenia-like psychosis: a Swedish population-based cohort study". Psychological Medicine: 1–9. doi:10.1017/S0033291721002003. PMID 34030526.
- ^ Costello, Harry (2019). "Systematic review and meta-analysis of the association between peripheral inflammatory cytokines and generalised anxiety disorder". BMJ Open. 9 (7): e027925. doi:10.1136/bmjopen-2018-027925. PMID 31340964.
- ^ Hazan, Jemma (2024). "Clinical utility of cerebrospinal fluid biomarkers in the evaluation of cognitive impairment: a systematic review and meta-analysis". JAMA Neurology. 81 (5): e123456. doi:10.1001/jamaneurol.2024.1092. PMID 38521879.
- ^ Satake, Yuto (2025). "A Week With a Conversational Large Language Model Companion Robot". The American Journal of Geriatric Psychiatry. 33 (7): 799–800. doi:10.1016/j.jagp.2024.12.012.
- ^ "Layla". X (formerly Twitter). 21 June 2023. Retrieved 28 June 2025.
- ^ Gale, Colin; Howard, Robert (2003). Presumed Curable: An Illustrated Casebook of Victorian Psychiatric Patients in Bethlem Hospital. Wrightson Biomedical Publishing. ISBN 9789492811158.
- ^ "Rob Howard on Breakdown". Channel 4. Retrieved 28 June 2025.
- ^ "Warwick Davis". Our Media Ltd. Retrieved 28 June 2025.
- ^ "Prof Rob Howard on BBC Breakfast". X (formerly Twitter). 12 June 2025. Retrieved 28 June 2025.
- ^ "Bethlem Museum of the Mind – Charity Commission register". Charity Commission for England and Wales. Retrieved 28 June 2025.
- ^ "Prizes and Bursaries – Faculty of Old Age Psychiatry". Royal College of Psychiatrists. Retrieved 28 June 2025.