Defenuron

Defenuron
	Skeletal formula of defenuron
Names
	Preferred IUPAC name 1-methyl-3-phenylurea
	Other names N-methyl-N'-phenylurea; N-phenyl-N'-methylurea; Desfenuron;
Identifiers
CAS Number	1007-36-9;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:157705;
ChEMBL	ChEMBL584381;
ChemSpider	13280;
ECHA InfoCard	100.151.228
EC Number	622-469-6;
KEGG	C22322;
PubChem CID	13880;
UNII	11YB479454;
CompTox Dashboard (EPA)	DTXSID1074416 ;
	InChI InChI=1S/C8H10N2O/c1-9-8(11)10-7-5-3-2-4-6-7/h2-6H,1H3,(H2,9,10,11) Key: SQBHGDSDVWCPHN-UHFFFAOYSA-N;
	SMILES CNC(=O)NC1=CC=CC=C1;
Properties
Chemical formula	C8H10N2O
Molar mass	150.181 g·mol−1
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H317, H318
Precautionary statements	P261, P264+P265, P272, P280, P302+P352, P305+P354+P338, P317, P321, P333+P317, P362+P364, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Defenuron is an obsolete herbicide. Its formula is C₈H₁₀N₂O.^[1] It is an urea herbicide and was once produced as a wettable powder to control undesirable grasses and broad-leaved plants in a variety of crops.^[2] It enters plants via diffusion and moves through the xylem.^[3] It is highly water-soluble, is of low toxicity to fish, and does not pose a significant health hazard to mammals^[2] or to Japanese quail.^[4]

References

^ "1-Methyl-3-phenylurea". PubChem. National Center for Biotechnology Information. Retrieved May 19, 2025.
^ ^a ^b "Defenuron (Ref: IPO 4328)". Pesticide Properties Database. 18 May 2025. Retrieved 19 May 2025.
^ Grimm, Eckhard; Neumann, Stefanie; Jacob, Friedrich (1985-01-01). "Transport of Xenobiotics in Higher Plants II. Absorption of Defenuron, Carboxyphenylmethylurea, and Maleic Hydrazide by Isolated Conducting Tissue of Cyclamen". Biochemie und Physiologie der Pflanzen. 180 (5): 383–392. Bibcode:1985BioPP.180..383G. doi:10.1016/S0015-3796(85)80089-5. ISSN 0015-3796.
^ Paulov, S. (1977). "[Effects of herbicides (Gramoxone and Defenuron) on the development and protein levels of quail (Coturix coturix japonica)]". Veterinarni Medicina (in Slovak). 22 (7): 413–419. ISSN 0375-8427. PMID 411224.

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[1] "1-Methyl-3-phenylurea". PubChem. National Center for Biotechnology Information. Retrieved May 19, 2025.

[ppdb-2] "Defenuron (Ref: IPO 4328)". Pesticide Properties Database. 18 May 2025. Retrieved 19 May 2025.

[3] Grimm, Eckhard; Neumann, Stefanie; Jacob, Friedrich (1985-01-01). "Transport of Xenobiotics in Higher Plants II. Absorption of Defenuron, Carboxyphenylmethylurea, and Maleic Hydrazide by Isolated Conducting Tissue of Cyclamen". Biochemie und Physiologie der Pflanzen. 180 (5): 383–392. Bibcode:1985BioPP.180..383G. doi:10.1016/S0015-3796(85)80089-5. ISSN 0015-3796.

[4] Paulov, S. (1977). "[Effects of herbicides (Gramoxone and Defenuron) on the development and protein levels of quail (Coturix coturix japonica)]". Veterinarni Medicina (in Slovak). 22 (7): 413–419. ISSN 0375-8427. PMID 411224.

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