Delta-8-THCM
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| Formula | C22H32O2 |
| Molar mass | 328.496 g·mol−1 |
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Delta-8-THCM (O-Methyl-Δ8-THC) is a chemical compound related to phytocannabinoids found in Cannabis. It has been sold as a designer drug, first identified in Sweden in June 2024.[1] However, it is a known compound which has been well established to almost entirely lack cannabinoid-like effects in mice, rats and monkeys,[2][3] unlike the dimethylheptyl analogue L-759,633 which is a selective agonist for CB2 and has antiinflammatory but not psychoactive effects.[4]
See also
[edit]References
[edit]- ^ "European Drug Report 2025 – Full Book" (PDF). European Union Drugs Agency (euda.europa.eu). 6 June 2025.
- ^ Mechoulam R, Edery H (1973). "Structure-Activity Relationships in the Cannabinoid series.". In Mecoulam R (ed.). Marijuana Chemistry, Pharmacology, Metabolism, and Clinical Effects. New York: Academic Press. pp. 101–136.
- ^ Compton DR, Prescott WR, Martin BR, Siegel C, Gordon PM, Razdan RK (November 1991). "Synthesis and pharmacological evaluation of ether and related analogues of delta 8-, delta 9-, and delta 9,11-tetrahydrocannabinol". Journal of Medicinal Chemistry. 34 (11): 3310–3316. doi:10.1021/jm00115a023. PMID 1659638.
- ^ Ross RA, Brockie HC, Stevenson LA, Murphy VL, Templeton F, Makriyannis A, et al. (February 1999). "Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656, and AM630". British Journal of Pharmacology. 126 (3): 665–672. doi:10.1038/sj.bjp.0702351. PMC 1565857. PMID 10188977.
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