User:Niki0930/sandbox
Importance of Coenzyme B in Methanogenesis
Coenzyme B is an important component in the terminal step of methane biogenesis.[1] It acts as a two electron-donor to reduce coenzyme M (methyl-coenzyme) into two molecules a methane and a heterodisulfide.[2] Two separate experiment that were performed, one with coenzyme B and other without coenzyme B, indicated that using coenzyme B before the formation of the methane molecule, results in a more efficient and consistent bond cleavage.[3]
 | This is a user sandbox of Niki0930. You can use it for testing or practicing edits. This is not the place where you work on your assigned article for a dashboard.wikiedu.org course. Visit your Dashboard course page and follow the links for your assigned article in the My Articles section. |
- ^ Dey, Mishtu; Li, Xianghui; Kunz, Ryan C; Ragsdale, Stephen W (2010-12-22). "Detection of Organometallic and Radical Intermediates in the Catalytic Mechanism of Methyl-Coenzyme M Reductase Using the Natural Substrate Methyl-Coenzyme M and a Coenzyme B Substrate Analogue". Biochemistry (Easton). 49 (51): 10902–10911. doi:10.1021/bi101562m.
- ^ Cedervall, Peder E; Dey, Mishtu; Pearson, Arwen R; Ragsdale, Stephen W; Wilmot, Carrie M (2010-07-22). "Structural Insight into Methyl-Coenzyme M Reductase Chemistry Using Coenzyme B Analogues". Biochemistry (Easton). 49 (35): 7683–7693. doi:10.1021/bi100458d.
- ^ Horng, Yih-Chern; Becker, Donald F; Ragsdale, Stephen W (2001-10-30). "Mechanistic Studies of Methane Biogenesis by Methyl-Coenzyme M Reductase: Evidence that Coenzyme B Participates in Cleaving the C−S Bond of Methyl-Coenzyme M". Biochemistry (Easton). 40 (43): 12875–12885. doi:10.1021/bi011196y.