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[[Glue|Amongus in Glue|oldid=9788131]]


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Hopefully by tomorrow I will have everything done, to be able to get back to the surface (to cat: Inflammation)! :)

Disambig! (log is not Special:Contributions!) User Log (last 50,000 entries)[1] (User log) Archived[1] Special:log/Catcus_DeDemowwy (^ but regular)

(current heart-related template fix) dupe content in template:
  • (archive)
  • archive
[(https://simple.wikipedia.org/w/index.php?title=User:MdWikiBot/Caesarean_section User:MdWikiBot/C_section)] (article) (found also on [(https://simple.wikipedia.org/wiki/User:MdWikiBot/Caesarean_section) Userːhttps://simple.wikipedia.org/wiki/User:Mr._Ibrahem/Caesarean_section)]
Caesarean section
A team performing a caesarean section[2]
Other namesC-section, cesarean section, caesarean delivery
ICD-10-PCS10D00Z0
ICD-9-CM74
MeSHD002585
MedlinePlus002911

Caesarean section, also known as C-section, or caesarean delivery, is the use of surgery to deliver babies.[3] A caesarean section is often necessary when a vaginal delivery would put the baby or mother at risk.[3] Reasons for this may include obstructed labor, twin pregnancy, high blood pressure in the mother, breech birth, or problems with the placenta or umbilical cord.[3][4] A caesarean delivery may be performed based upon the shape of the mother's pelvis or history of a previous C-section.[3][4] A trial of vaginal birth after C-section may be possible.[3] The World Health Organization recommends that caesarean section be performed only when medically necessary.[4][5] Some C-sections are performed without a medical reason, upon request by someone, usually the mother.[3]

A C-section typically takes 45 minutes to an hour.[3] It may be done with a spinal block, where the woman is awake, or under general anesthesia.[3] A urinary catheter is used to drain the bladder, and the skin of the abdomen is then cleaned with an antiseptic.[3] An incision of about 15 cm (6 inches) is then typically made through the mother's lower abdomen.[3] The uterus is then opened with a second incision and the baby delivered.[3] The incisions are then stitched closed.[3] A woman can typically begin breastfeeding as soon as she is out of the operating room and awake.[6] Often, several days are required in the hospital to recover sufficiently to return home.[3]

C-sections result in a small overall increase in poor outcomes in low-risk pregnancies.[4] They also typically take longer to heal from, about six weeks, than vaginal birth.[3] The increased risks include breathing problems in the baby and amniotic fluid embolism and postpartum bleeding in the mother.[4] Established guidelines recommend that caesarean sections not be used before 39 weeks of pregnancy without a medical reason.[7] The method of delivery does not appear to have an effect on subsequent sexual function.[8]

In 2012, about 23 million C-sections were done globally.[9] The international healthcare community has previously considered the rate of 10% and 15% to be ideal for caesarean sections.[5] Some evidence finds a higher rate of 19% may result in better outcomes.[9] More than 45 countries globally have C-section rates less than 7.5%, while more than 50 have rates greater than 27%.[9] Efforts are being made to both improve access to and reduce the use of C-section.[9] In the United States as of 2017, about 32% of deliveries are by C-section.[10] The surgery has been performed at least as far back as 715 BC following the death of the mother, with the baby occasionally surviving.[11] Descriptions of mothers surviving date back to 1500.[11] With the introduction of antiseptics and anesthetics in the 19th century, survival of both the mother and baby became common.[11]

  • Pregnancy infobo  Done
    • The infobox obstetrical procedures needs to be complete one time before looking at whether the pregnancy template should be deleted or what merges and how pages will contain these templates. The pages (that exist) are done, and there are only a few pages (regarding pregnancy - anatomy) to add to the template, as I have been adding fields to the template - to get it finished
  • Archives
Main Page   Talk   Members    

collapses:

Search on Logs or Cat:Quick del request; find important articles (e.g: Notable, valid, Important); then

  1. Simplify
  2. Create
  3. Log it here.

Rescued So far

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  1. Germany_at_the_Winter_Olympics /  Done by Cat and Log
  2. Cinnamoroll /  Done by Cat and Log
  3. Slushy /  Done by Cat and Log
  4. Caltrain /  Done by Cat and Log
  5. Women in the Victorian era / Done by Cat and Log
  6. Life skills / yellow tickY Partly done by Deletion Request  Done of the RfA resulting in "Keep"
  7. Joseph Henry/  Done by Cat
  8. United Launch Alliance /  Done by searching on QD_logs.
  9. Hardoi district /  Done by Log
  10. James Coco /  Done by Log
  11. Wheelchair Race /  Done by Log
  12. François Mignet /  Done by Log
  13. Cartoon Network Studios /  Done by Log
  14. San Pedro, California /  Done by Log
  15. Edward Harrison Taylor /  Done
  16. John Lyly /  Done by Log
  17. Kylie (name) /  Done by Cat
  18. Cardiovascular fitness /  Done by Cat
  19. Prey (2022 movie) /  Done by Cat
  20. Washington Territory /  Done by Cat
  21. Theodor_Wolf /  Done by Log
  22. Norvège /  Done by RC patrolling
  23. Svastika /  Done by RC patrolling
  24. Lean (drug) /  Done by RC patrolling
  25. Gloria_Fuertes /  Done by Log
  26. Max_the_Mighty /  Done by Log
  27. Chin Han /  Done by Log
  28. Bill_Mallon /  Done by Log
  29. Pastoralism /  Done by Log
  30. Quill_Award /  Done by Log
  31. The_Wrong_Trousers /  Done by Log
  32. South_Wilts_Grammar_School /  Done by Log
  33. FuboTV /  Done by Log
  34. 1939 Erzincan earthquake /  Done by Log

References

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  1. ↑ 1.0 1.1 "Main public logs - Simple English Wikipedia, the free encyclopedia". web.archive.org. 2025-04-27. Retrieved 2025-04-27.
  2. ↑ Fadhley, Salim (2014). "Caesarean section photography". WikiJournal of Medicine. 1 (2). doi:10.15347/wjm/2014.006.
  3. ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 "Pregnancy Labor and Birth". Office on Women’s Health, U.S. Department of Health and Human Services. 1 February 2017. Archived from the original on 28 July 2017. Retrieved 15 July 2017. This article incorporates text from this source, which is in the public domain.
  4. ↑ 4.0 4.1 4.2 4.3 4.4 "Safe Prevention of the Primary Cesarean Delivery". American Congress of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine. March 2014. Archived from the original on 2 March 2014. Retrieved 20 February 2014.
  5. ↑ 5.0 5.1 "WHO Statement on Caesarean Section Rates" (PDF). 2015. Archived (PDF) from the original on 1 May 2015. Retrieved 6 May 2015.
  6. ↑ Lauwers, Judith; Swisher, Anna (2010). Counseling the Nursing Mother: A Lactation Consultant's Guide. Jones & Bartlett Publishers. p. 274. ISBN 9781449619480. Archived from the original on 11 September 2017.
  7. ↑ American Congress of Obstetricians and Gynecologists, "Five Things Physicians and Patients Should Question", Choosing Wisely: an initiative of the ABIM Foundation, American Congress of Obstetricians and Gynecologists, archived from the original on 1 September 2013, retrieved 1 August 2013
  8. ↑ Yeniel, AO; Petri, E (January 2014). "Pregnancy, childbirth, and sexual function: perceptions and facts". International Urogynecology Journal. 25 (1): 5–14. doi:10.1007/s00192-013-2118-7. PMID 23812577.
  9. ↑ 9.0 9.1 9.2 9.3 Molina, G; Weiser, TG; Lipsitz, SR; Esquivel, MM; Uribe-Leitz, T; Azad, T; Shah, N; Semrau, K; Berry, WR; Gawande, AA; Haynes, AB (1 December 2015). "Relationship Between Cesarean Delivery Rate and Maternal and Neonatal Mortality". JAMA. 314 (21): 2263–70. doi:10.1001/jama.2015.15553. PMID 26624825.
  10. ↑ "Births: Provisional Data for 2017" (PDF). CDC. May 2018. Archived (PDF) from the original on 17 May 2018. Retrieved 18 May 2018.
  11. ↑ 11.0 11.1 11.2 Moore, Michele C.; Costa, Caroline M. de (2004). Cesarean Section: Understanding and Celebrating Your Baby's Birth. JHU Press. p. Chapter 2. ISBN 9780801881336. Archived from the original on 27 July 2020. Retrieved 29 July 2020.

Category:Mdwiki Translation Dashboard articles


(current generic template project) fix content in template: [[Template:Deathslist boilerplate]]

I have List of deaths starts with:

To begin with, I want to do these articles I have already cleaned up. I have been experimenting with different ways of doing the lists, within the edits doing the lists. This list is mostly just to place the start of the contents (relating to the current project) such as when a template/navbox goes there.

  • I have decades (i.e. I will probably do 2024, then edit the deaths in 2000 (decade) articles to do if anyone would like to pick a decade they like and do it
    • Pick a decade you like sounds silly and it is. if someone wants to edit a number specifically of these articles to help out then it may as well go to a level the editor is comfortable with and do all the related articles, instead of random ones. This can be years (list every month in the year), decades (every year in the decade) and so on if we have them on the larger side. The level can be months (each day on the month - but there are more) on the smaller size, or individual people lower than that. But it is good to edit within a group you can find when editing years dates, to say again

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change source section

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https://commons.wikimedia.org/wiki/File:AS_trask.jpg[purge] (Link to file) (red link?)


Useful references and reliable sources (Wikiessay) https://en.wikipedia.org/wiki/Wikipedia:WikiProject_Medicine/Lists_of_pages/Non-articles


Gray's anatomy

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  • Just a patten (n of 2) I found in the book:
    • 1: In the female, the urethra is derived entirely from the vesico-urethral region of the cloaca, including the dorsal region derived from the meso¬ nephric ducts. It is homologous with the part of the prostatic urethra proximal to the orifices of the prostatic utricle and the ejaculatory ducts. The region of the early urethra remains open to form the vestibule, into which the definitive urethra and vagina open (see Fig. 72.20). It is
    • For many years, it was believed that the absorption of the mesone¬ phric ducts into the urogenital sinus contributed a mesodermal epithe¬ lium into the endodermal bladder, limited to the trigone and the dorsal wall of the proximal half of the prostatic urethra to the opening of the prostatic utricle and ejaculatory ducts, or its female homologue, the whole female urethral dorsal wall.
    • 2: In the male, the prostatic urethra proximal to the orifice of the pro¬ static utricle is derived from the vesico-urethral part of the cloaca and the incorporated caudal ends of the mesonephric ducts.
  • page 1287 (section above the refs) mentions spermatic ducts only twice or three times. (I should read that section)
    • which is page 1778 electronically

(within) mesonephros, Gray's

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each tubule first appears as a condensation of mesenchyme cells, which epithelialize and form a vesicle.

(One end) at the caudal end of the ridge, it projects into the cavity of the coelom in the substance of a mesonephric fold (see Fig. 72.3). As the mesonephric ducts from each side approach the uro genital sinus, the two mesonephric folds fuse, between the bladder ventrally and the rectum dorsally, forming a transverse partition across the cavity of the pelvis, which is somewhat inappropriately called the genital cord (see Fig. 72.3)

Meconium (first faeces of newborn)

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(Scale: 5 cm left to right.) (newborn) babies poop a lot! 3 in 12 hours = Meconium from 12-hour-old newborn. Babies third bowel movement
(Scale: 5 cm left to right.) (newborn) babies poop a lot! 3 in 12 hours
= Meconium from 12-hour-old newborn. Babies third bowel movement
(newborn) babies poop a lot! 3 in 12 hours

= Meconium from 12-hour-old newborn - Babies third bowel movement. Scale: 5 cam left to right.

x86 Operating Systems

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Operating systems in magenta run only on x86 processors. Operating systems in blue originated on x86 but have since been made for other processors as well. Operating systems in orange did not originate on x86 and were ported to x86.

marsupium.

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In contrast to Eutheria (placentals), marsupials have an incomplete PLACENTA

Important MeSH Note 2005; see KANGAROOS 1991-2004, see MARSUPIALIA 1975-1990, infraclass of MAMMALS, also called Metatheria

MeSH B01.050.050.136


MeSH D000833

MeSH B01.050.050.293

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by mother or by bottle; coord with specific suckling; NIM when exper animal; suckling of animals (the act, as in the eff of suckling on animal physiol) goes under LACTATION; do not forget also to check tag ANIMALS|Young, unweaned mammals. Refers to nursing animals whether nourished by their biological mother, foster mother, or bottle fed.}}

Annotation suckled by mother or by bottle; coord with specific suckling; NIM when exper animal; suckling of animals (the act, as in the eff of suckling on animal physiol) goes under LACTATION; do not forget also to check tag ANIMALS Scope Note Young, unweaned mammals. Refers to nursing animals whether nourished by their biological mother, foster mother, or bottle fed.

References

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{{self|cc-zero}} Category:Ocular fundus


Impact frame (interesting wikicode)

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Showing impact data for Catcus DeMeowwy

Please enable JavaScript to view this component.

Licensing

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References ↑

McKenna KA, Fogleman CD (August 2021). "Dysmenorrhea". Am Fam Physician. 104 (2): 164–170. PMID 34383437. American College of Obstetricians and Gynecologists (Jan 2015). "FAQ046 Dynsmenorrhea: Painful Periods" (PDF). Archived (PDF) from the original on 27 June 2015. Retrieved 26 June 2015.


The heart (Anatomy of the human heart)

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Find more about
Heart
at Wikipedia's sister projects
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  • General
Anatomy_of_the_arteries_of_the_human_body_-_descriptive_and_surgical,_with_the_descriptive_anatomy_of_the_heart_(1881)_(14764835715)
Anatomy_of_the_arteries_of_the_human_body_-_descriptive_and_surgical,_with_the_descriptive_anatomy_of_the_heart_(1881)_(14764835715)
(above) Anatomy of the arteries of the human body - descriptive and surgical, with the descriptive anatomy of the heart (1881)[1] (14764835715).jpg
  • (Surface (base) cont.)
    • The surface of Mars looks a bit like a heart (and an angel)
Perspective_view-_An_angel_and_heart_on_Mars_ESA22393107
Perspective_view-_An_angel_and_heart_on_Mars_ESA22393107
(above) a Perspective view- An angel and heart on Mars ESA22393107.jpeg (from [2])

(AI): The apex of the heart is the lowest, most pointed part of the heart, located at the inferolateral region of the left ventricle. It sits posterior to the left 5th intercostal space, typically about 9 cm from the median plane[3]. (en Wiki): The heart is cone-shaped, with its base positioned upwards and tapering down to the apex.[4]

The human heart is in the middle of the thorax, with its apex pointing to the left.
The human heart is in the middle of the thorax, with its apex pointing to the left.
(above) The human heart is in the middle of the thorax, with its apex pointing to the left.[5] (commons.png)

a sulcus (pl.: sulci) is a furrow or fissure (Latin fissura, pl.: fissurae), of which the heart has many:

They are not just in the heart but the brain too.

Rotating image of human brain, illustrating the lateral sulcus in the brain.


Medical_diagnosis_for_the_student_and_practitioner_(1922)_(14784496995)
Medical_diagnosis_for_the_student_and_practitioner_(1922)_(14784496995)
(above) Medical diagnosis for the student and practitioner (1922)[6] (14784496995).jpg
(above) (text appearing before the image): It maycease for short periods, moreover, to beat at all, in which case syncopalattacks may occur and thus round out the classical Adams-Stokessyndrome. The Pace Maker of the Heart.—Whence come the rhythmic impulses whichinduce coordinate contraction of the auricles and ventricles? There is a normal point of maximum irritability represented by a networkof specialized muscle cells richly supplied with nerves and imbedded in theupper anterior end of the sulcus terminalis, which sulcus runs from the in-ferior vena cava to the junction of the superior vena cava with the rightauricular appendix. *W. H. Gaskell of Cambridge University, England, actually demonstrated bothmyogenic conduction and heart block in the frog and tortoise in the year 1883. THE EXAMINATION OF THE HEART 467 This is the sino-auriciilar node of Keith and Flack which, from its stationin the wall of the right auricle at the mouth of the superior vena cava, normally initiates each contraction of the heart.

Sulcus runs from the inferior vena cava to the junction of the superior vena cava with the right auricular appendix in this image.

  • (Sulci cont.)
    • Sulci is continued in a following section outside of general (surface).
  • (General cont.)
    • Borders

The two borders of the heart are right border of heart and left margin of heart (en Wiki).

Right border of heart
Details
Identifiers
Latinmargo dexter cordis
Anatomical terminology
Gray492
Gray492
(above) Sternocostal surface of heart. (Right margin visible but not labeled.) (1982)[7][8] (gray492.png)
Left border of heart
Details
Identifiers
Latinmargo obtusus
Anatomical terminology
Anatomical structures captured from the app 3D Heart Anatomy
Anatomical structures captured from the app 3D Heart Anatomy
(above) left border of heart.
  • (General cont.)
    • Base section end / (General) Internal:
    • Atria (Atrium)

deleted information

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  • backup:
Michellamine (en.Wiki) from user Jshepeck (en. Wiki) user page/Michellamine
Catcus DeMeowwy
Names
IUPAC name
(1R,3R,1’R,3’R)-5,5’-(1,1’-dihydroxy-8,8’-dimethoxy-6,6’-dimethyl-2,2’-binaphthalene-4,4’-diyl)bis(1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline-6,8-diol)
Identifiers
3D model (JSmol)
ChemSpider
  • Oc1c8c(c(c(O)c1)c2cc(c(O)c3c2cc(cc3OC)C)c7c(O)c4c(cc(cc4OC)C)c(c5c(O)cc(O)c6c5C[C@H](N[C@@H]6C)C)c7)C[C@H](N[C@@H]8C)C
Properties
C46H48N2O8
Molar mass 756.882
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):


Michellamine is an atropisomeric alkaloid which has been found as a strong anti-HIV enzyme. It was discovered in the leaves of the Ancistrocladus korupensis which is a member of the Triphyophyllum peltatum found in Cameroon.[9] There are 3 michellamines represented as A, B, and C, however, Michellamine B is the most active against the NID-DZ strain of HIV-2.[10]

Occurance

Michellamine A and B alkaloids are found to naturally occur in the leaves of the Ancistrocladus korupensis which is a member of the Triphyophyllum peltatum found in Cameroon. Bioactive chemical substances including alkaloids, tannins, and saponin are found in several plants in their roots, leaves, stems, flowers, or bark. Therapeutic chemicals have been found in various plants to treat diseases such as malaria, diabetes, and cancers.[11]

Synthesis

There are 2 methods explored to synthesize Michellamines A and B. The first one, originally synthesized in 1994, is a retrosynthesis that leads to a biomimetic pathway that uses the construction of naphthalene/isoquinoline bonds before the naphthalene/naphthalene axis. The second method, originally synthesized only a few montes after the first method, is a complementary pathway that would use the naphthalene/naphthalene axis after it is created and add the 2 isoquinoline moieties.[12]

Medical Use

The main use of Michellamines are in anti-HIV medications. It is found to inhibit viral replication of the Protein kinase C and virus-induced cellular fusion. It has a broad range of effectiveness across most HIV strains and especially in the strain HIV-2, which is found primarily in and around Cameroon.[13]

References

  1. ↑ https://archive.org/stream/anatomyofarterie00powe/anatomyofarterie00powe#page/n18/mode/1up
  2. ↑ https://www.esa.int/ESA_Multimedia/Images/2020/12/Perspective_view_An_angel_and_heart_on_Mars
  3. ↑ https://www.kenhub.com/en/library/anatomy/apex-of-the-heart
  4. ↑ http://cnx.org/content/m46676/latest/?collection=col11496/latest
  5. ↑ "Gray's Anatomy of the Human Body – 6. Surface Markings of the Thorax". Bartleby.com. Archived from the original on 20 November 2010. Retrieved 2010-10-18.
  6. ↑ https://archive.org/stream/medicaldiagnosi00gree/medicaldiagnosi00gree#page/n494/mode/1up
  7. ↑ http://www.bartleby.com/107/
  8. ↑ http://www.bartleby.com/107/illus492.html
  9. ↑ Schlauer, Jan; Rückert, Markus; Wiesen, Birgit; Herderich, Markus; Assi, Laurent Aké; Haller, René D.; Bär, Sabine; Fröhlich, Kai-Uwe; Bringmann, Gerhard (1). "Characterization of Enzymes fromAncistrocladus(Ancistrocladaceae) andTriphyophyllum(Dioncophyllaceae) Catalyzing Oxidative Coupling of Naphthylisoquinoline Alkaloids to Michellamines". Archives of Biochemistry and Biophysics. 350 (1): 87–94. doi:10.1006/abbi.1997.0494. PMID 9466824. {{cite journal}}: Check date values in: |date= and |year= / |date= mismatch (help); Unknown parameter |month= ignored (help)
  10. ↑ Zhang, Heping; Zembower, David E.; Chen, Zhidong (NaN undefined NaN). "Structural analogues of the michellamine anti-HIV agents. Importance of the tetrahydroisoquinoline rings for biological activity". Bioorganic & Medicinal Chemistry Letters. 7 (20): 2687–2690. doi:10.1016/S0960-894X(97)10057-9. {{cite journal}}: Check date values in: |date= and |year= / |date= mismatch (help); Unknown parameter |month= ignored (help)
  11. ↑ Okigbo, R. N. (February 2009). [[[:Template:Predatory]] "Advances in selected medicinal and aromatic plants"]. Journal of Medicinal Plants Research. 3 (2): 86–95. Retrieved April 6, 2011. {{cite journal}}: Check |url= value (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)CS1 maint: date and year (link)
  12. ↑ Bringmann, Gerhard; Götz, Roland; Keller, Paul A.; Walter, Rainer; Boyd, Michael R.; Lang, Fengrui; Garcia, Alberto; Walsh, John J.; Tellitu, Imanol; Bhaskar, K. Vijaya; Kelly, T. Ross (NaN undefined NaN). "A Convergent Total Synthesis of the Michellamines". The Journal of Organic Chemistry. 63 (4): 1090–1097. doi:10.1021/jo971495m. {{cite journal}}: Check date values in: |date= and |year= / |date= mismatch (help); Unknown parameter |month= ignored (help)
  13. ↑ White, E.Lucile; Chao, Wan-ru; Ross, Larry J.; Borhani, David W.; Hobbs, Peter D.; Upender, Velaparthi; Dawson, Marcia I. (1). "Michellamine Alkaloids Inhibit Protein Kinase C". Archives of Biochemistry and Biophysics. 365 (1): 25–30. doi:10.1006/abbi.1999.1145. PMID 10222035. {{cite journal}}: Check date values in: |date= and |year= / |date= mismatch (help); Unknown parameter |month= ignored (help)
[ [:Category:Alkaloids]]
  • Backup:
Jean-Pierre Lecocq (en. Wiki) from User Grey_Geezer (en.Wiki) user page/Genpool
Jean-Pierre Lecocq (17 July 1947 – 20 January 1992) was a Belgian molecular biologist and entrepreneur.

Education

Lecocq was born in Gosselies/Charleroi but grew up in Nivelles. In 1965 he received a scholarship to study Chemistry at the the Free University of Brussels. In 1969 he graduated with honors (avec grande distinction). Starting in 1969, he worked on his doctoral thesis in the laboratory of Prof. René Thomas, Département de Biologie Moléculaire, on the interactions between a prokaryote (Escherichia coli) and a virus (bacteriophage lambda). He identified new bacterial genes, which lead to bacterial lysogenic cycle and lysis and he analyzed mutants of RNA polymerase. From 1974 to 1975 Lecocq was drafted into the military, but returned to research to finish his PhD in 1975 with summa cum laude (la plus grande distinction). Until early 1977, he continued working at the Free University in Brussels as a post-doc (Chargé de Recherche) with short research stays in the USA (Madison, Wisconsin) and Canada (Laval University, Quebec).

Professional career

From 1977 to 1980, in the early years of the rapidly developing genetic engineering, Lecocq was project manager in the Department of Genetics of the pharmaceutical company SmithKline RIT, in Rixensart, Belgium, where he set up a molecular biology laboratory and directed the research on vaccines against enteropathogenic E. coli strains, and hepatitis B virus.

In 1980 he became Scientific Director of Transgène, one of the first biotech companies in France, which was founded in Strasbourg in 1979 by the initiative of Prof. Pierre Chambon and Dr. Philippe Kourilsky, the goal beeing to develop new technologies in biomedical research for industrial applications. In 1984, Lecocq became Vice President and in 1990 President of Transgène.

After Transgène was acquired in 1991 by the Mérieux group, Lecocq also became Corporate Director of Research and Development of the Pasteur-Merieux-Connaught Group, based in Lyon.

Jean-Pierre Lecocq died at age 44 in the crash of Air Inter Flight 148 on 20 January 1992 at Mont Sainte-Odile, Alsace. He is survived by his wife Mireille and two children.

Research

From 1980 until 1992 Lecocq established French and international collaborations between Transgène, academic institutions and industry.
Under his leadership secretory and non-secretory expression systems for the production of recombinant proteins in E. coli, Saccharomyces cerevisiae, Baculovirus and mammalian cells in cell culture were developed and recombinant virus technology was established. A Hybridoma Laboratory provided for the development of monoclonal antibodis for analyses ((ELISA) and immunoaffinity chromatography. Conventional as well as HPLC methods for downstream purification and analysis of the produced peptides, proteins and glycoproteins were established.
These technologies have been applied, among others, to the following projects: a new concept based on vaccinia virus for a rabies vaccine in the wild (Raboral, in November 1991 awarded with the Rhone Poulenc Prize for Innovation and used in several countries for the vaccination of foxes, and raccoons), recombinant versions of blood clotting factor VIII|factor VIII and Factor IX for the treatment of hemophilia A on behalf of the French blood transfusion service CNTS; vaccine candidates for schistosomiasis, toxoplasmosis and babesia canis; recombinant hirudin, α-1-antitrypsin, gamma-interferon and interleukins, and variants thereof, construction of virtually all recombinant proteins of HIV-1, HIV-2 and SIV for mechanistic studies and applications in diagnosis, and immunization; characterization of α-thrombin receptor, mechanisms of Cystic Fibrosis.

Publications

Between 1970 and 1991 Jean-Pierre Lecocq published 130 papers, 15 additional publications about subjects and projects initiated by Lecocq appeared from 1992 until 1995 postum.
In the following a selection of representative publications is listed:

  • J.P. Lecocq (doctoral thesis) Étude génétique et biochimique de la régulation de la transcription Dépt. de Biologie Moléculaire, Université Libre de Bruxelles (1975)
  • J.P. Lecocq, C. Dambly, R. Lathe, C. Babinet, A. Bailone, R. Devoret, A.M. Gathoye, H. Garcia, M. Dewilde and T. Cabezon Nomenclature and location of bacterial mutations modifying the frequency of lysogenisation of E.coli by lambdoïd phages Molec. Gen. Genet. 145, 63-64 (1976)
  • J.P. Lecocq, M. Zubowski and R. Lathe Cloning and expression of viral antigens in Escherichia coli and other microorganisms in: "Methods in Virology" (1984), 7, 121-172, K. Maramorosch, H. Koprowski, eds, Academic Press Inc, Orlando , Florida.
  • M. Courtney, S. Jallat, L.H. Tessier, A. Benavente, R.G. Crystal and J.P. Lecocq Synthesis in E. coli of alpha1-antitrypsin variants of therapeutic potential emphysema and thrombosis Nature 313, 149-151 (1985)
  • H. de la Salle, W. Altenburger, R. Elkaim, K. Dott, A. Dieterlé, R. Drillien, J.P. Cazenave, P. Tolstoshev and J.P. Lecocq Active gamma-carboxylated human factor IX expressed using recombinant DNA techniques Nature 316, 268-270 (1985)
  • R.P. Harvey, E. Degryse, L. Stefanie, F. Schamber, J.P. Cazenave, M. Courtney, P. Tolstoshev and J.P. LecocQ Clonig and expression of a cDNA coding for the anticoagulant hirudin from the bloodsucking leech, hirudo medicinalis Proc. Natl. Acad. Sci. USA, 83, 1084-1088 (1986)
  • A. Capron, R. Pierce, J.M. Balloul, J.M. Grzych, C. Dissous, P. Sondermeyer and J.P. Lecocq Protective antigens in experimental schistosomiasis Acta Tropica 44, 63-69 (1987)
  • G. Rautmann, M.P. Kieny, R. Brandely, K. Dott, M. Girard, L. Montagnier and J.P. Lecocq HIV-1 core proteins expressed from recombinant vaccinia viruses AIDS Res. Hum. Retroviruses (1989) 5, 147-57.
  • M.P. Kieny, J.P. Lecocq, M. Girard, Y. Rivière, L. Montagnier and R. Lathe Tailoring the human immunodeficiency virus envelope glycoprotein to improve immunogenicity in: Vaccines 89, R.A. Lerner, H. Ginsberg, R.M. Chanock, F. Brown, Cold Spring Harbor Laboratory, 177-183 (1989)
  • J.P. Van Eendenburg, M. Yagello, M. Girard, M.P. Kieny, J.P. Lecocq, E. Muchmore, P.N. Fultz, Y. Rivière, L. Montagnier and J.C. Gluckman Cell-mediated immune proliferative responses to HIV-1 of chimpanzees vaccinated with different vaccinia recombinant viruses AIDS Res. Hum. Retroviruses (1989) 5, 41-50.
  • T. Faure, A. Pavirani, P. Meulien, H. de la Salle, G. Mignot, H. van de Pol, M. Courtney and J.P. Lecocq Stable expression of coagulation factors VIII and IX in recombinant chinese hamster ovary cells Advances in Animal Cell Biology and Technology for Bioprocesses (1989), R.E. Spier, J.B. Griffiths, J. Stephenne, P.J. Crooy, Butterworths, England, 481-487.
  • M.F. Cesbron-Delauw, B. Guy, G. Torpier, R.J. Pierce, G. Lenzen, J.Y. Cesbron, H. Charif, P. Lepage, F. Darcy, J.P. Lecocq et al. Molecular characterization of a 23-kilodalton major antigen secreted by Toxoplasma gondii Proc. Natl. Acad. Sci. USA, 86 , 7537-7541 (1989)
  • B. Brochier, M.P. Kieny, F. Costy, P. Coppens, B. Bauduin, J.P. Lecocq, B. Languet, G. Chappuis, P. Desmettre, K. Afiademanyo, R. Libois and P.P. Pastoret Large-scale eradication of rabies using recombinant vaccinia-rabies vaccine Nature 354, 520-522 (1991)
  • M.A. Rosenfeld, W. Siegfried, K. Yoshimura, K. Yoneyama, M. Fukayama, L.E. Stier, P.K. Paakko, P. Gilardi, L.D. Stratford-Perricaudet, M. Perricaudet, S. Jallat, A. Pavirani, J.P. Lecocq and R.G. Crystal Adenovirus-Mediated transfer of a recombinant alpha-1-antitrypsin gene to the lung epithelium in vivo Science, 252, 431-434 (1991)
  • U.B. Rasmussen, V. Vouret-Craviari, S. Jallat, Y. Schlesinger, G. Pages, A. Pavirani, J.P. Lecocq, J. Pouyssegur and E. Van Obberghen-Schilling E. cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization FEBS Lett. 288 , 123-128 (1991)
  • J.M. Reichart, I. Petit, M. Legrain, J.L. Dimarq, E. Keppi, J.P. Lecocq, J.A. Hoffmann and T. Achstetter Expression and Secretion in Yeast of Active Insect Defensin, an Inducible Antibacterial Peptide from the Fleshfly Phormia terranovae Invert. Reprod. and Dev., 21, 15-24 (1992)
  • M.A. Rosenfeld, K. Yoshimura, B.C. Trapnell, K. Yoneyama, E.R. Rosenthal, W. Dalemans, M. Fukayama, J. Bargon, L.E. Stier, L.D. Stratford-Perricaudet, M. Perricaudet, W.B. Guggino, A. Pavirani, J.P. Lecocq and R.G. Crystal In vivo Transfer of the Human Cystic Fibrosis Transmembrane Conductance Regulator Gene to Airway Epithelium Cell, 68, 143-155 (1992)

Editorial boards

Lococq was on the editorial boards of the following journals:

Memberships

Lecocq was a member of the following organizations:

  • Société Belge de Biochimie since 1970
  • European Molecular Biology Organization(EMBO)since 1985
  • Conseil Scientifique des Institut National de la Recherche Agronomique (INRA) since 1986
  • Advisor of the World Health Organization (WHO) in Geneva since 1986
  • Comité National de Biochimie: Section des Représentants Français des Industries Biologiques et Biochimiques since 1986
  • Conseil Scientifique de l'Université Louis Pasteur, Strasbourg since 1986
  • Conseil Scientifique de l'Association Française de Médecine Préventive since 1986
  • Comité d'Orientation de la Délégation Régionale de l'ANVAR France since 1986
  • Comité Académique des Applications de la Science (CADAS) since 1988

Fondation Jean-Pierre Lecocq

To honor the achievements and the person, in 1992 the Fondation Jean-Pierre Lecocq was created, which since 1994 (and until the year 2020) awards a bi-annual prize for "new and significant research achievements in molecular biology and their application".

Bibliography

  • Orbituary in Molecular Microbiology (1992) 6 (11), S. 1577-1578
  • Orbituary in Gene (1992) 118 (1), S. 1-4
  • Archive of Transgène SA, Boulevard Gonthier d’Andernach, Parc d’Innovation, F-67405 Illkirch Graffenstaden Cedex, France.
{{Persondata |NAME= Lecocq, Jean-Pierre |ALTERNATIVE NAMES= |SHORT DESCRIPTION= [[Belgium|Belgian]] [[Molecular Biology|molecular biologist]] and [[Entrepreneur|entrepreneur]] |DATE OF BIRTH= 1947-07-17 |PLACE OF BIRTH= [[Gosselies]], [[Belgium]] |DATE OF DEATH= 1992-01-20 |PLACE OF DEATH= [[Mont Sainte-Odile]], [[Alsace]] }} {{DEFAULTSORT:Lecocq, Jean-Pierre}} [[:Category:Chemist]] [[:Category:Molecular Biologist]] [[:Category:Virologist]] [[:Category:Entrepreneur (France)]] [[:Category:HIV/AIDS researchers]] [[:Category:Belgian]] [[:Category:1947 births]] [[:Category:1992 deaths]] [[:Category:Man]] {{Personendaten |NAME=Lecocq, Jean-Pierre |ALTERNATIVNAMEN= |KURZBESCHREIBUNG=belgischer Molekularbiologe und Unternehmer |GEBURTSDATUM=17. Juli 1947 |GEBURTSORT=Gosselies |STERBEDATUM=20. Januar 1992 |STERBEORT=Mont Sainte-Odile }}
  • archive
==Copyright==

Still follow up on this

"STD incidence rates remain high in most of the world, despite diagnostic and therapeutic advances that can rapidly render patients with many STDs noninfectious and cure most. In many cultures, changing sexual morals and oral contraceptive use have eliminated traditional sexual restraints, especially for women, and both physicians and patients have difficulty dealing openly and candidly with sexual issues. Additionally, development and spread of drug-resistant bacteria (e.g., penicillin-resistant gonococci) makes some STDs harder to cure. The effect of travel is most dramatically illustrated by the rapid spread of the AIDS virus (HIV-1) from Africa to Europe and the Americas in the late 1970s.[1]

Commonly reported prevalences of STIs among sexually active adolescent girls both with and without lower genital tract symptoms include chlamydia (10–25%), gonorrhea (3–18%), syphilis (0–3%), Trichomonas vaginalis (8–16%), and herpes simplex virus (2–12%).[source?] Among adolescent boys with no symptoms of urethritis, isolation rates include chlamydia (9–11%) and gonorrhea (2–3%).[source?] "

May be from [1] Doc James (talk · contribs · email) 23:23, 27 January 2017 (UTC)

Yup a copyright problem. Doc James (talk · contribs · email) 03:56, 28 January 2017 (UTC)
Yes, it was added in this edit in 2006. The editor who added it also included a link to that source, so it isn't a case of reverse copyvio. Hut 8.5 21:51, 9 February 2017 (UTC)

References

  1. ↑ Mary-Ann Shafer; Anna-Barbara Moscicki (2006). "Sexually Transmitted Infections, 2006": 1–8. {{cite journal}}: Cite journal requires |journal= (help)
thankyou @@Doc James :3|
  • archive
Catcus DeMeowwy
File:CaptainMorganStrait.jpg
The Captain Morgan technique for hip reduction
Other namesReduction of the hip
SpecialtyOrthopedics
ComplicationsAvascular necrosis of the hip, sciatic nerve injury[1]

Hip reduction is a number of techniques used to restore a dislocated hip.[1] It should be carried out soon after the diagnosis is confirmed.[1][3] In those who have an associated fracture, surgical reduction may be required.[1] Complications of delay may include avascular necrosis of the hip and sciatic nerve injury.[1]

It is generally carried out under procedural sedation and analgesia (PSA) with the person on their back.[1] The hip and knee are than bent to 90 degrees while an assistant pushes downward on the pelvis.[1] Techniques than include some combination traction-countertraction and internal and external rotation.[1] If this is not sufficient a sheet may be used to pull the upper thigh outwards.[1]

Following the procedure further X-rays or a CT scan should be done to verify reduction and rule out complications.[1][2] Some recommend that an abduction pillow is than be placed between a persons legs.[1] Following this partial weight-bearing with crutches is recommended for 4 to 6 weeks.[2] The first techniques to reduce a hop without surgery were described in 1870.[2]

References

[change | change source]


  • archive
Catcus DeMeowwy
12.3 GA / 8 Fr, 14 GA / 6.3 Fr, and 16 GA / 5 Fr needles used for the procedure
Other namesNeedle decompression[4]
SpecialtyEmergency medicine
ComplicationsBleeding, infection, lung or diaphragm injury[4]

Needle thoracostomy (NT) is a procedure used in the initial treatment of a suspected tension pneumothorax.[4] It is generally followed by placement of a chest tube.[4] Finger thoracostomy; however, may be preferred over needle thoracostomy.[7] It is a type of thoracostomy, along with chest tubes and catheter thoracostomy.[5]

Typically the procedure is carried out in the 2nd intercostal space mid clavicular line or the 4th intercostal space anterior axillary line.[4][8] If sufficient time is present, the area may be cleaned with chlorhexidine and local anesthetic injected.[4] A 12, 14, or 16 gauge hollow needle and catheter is than placed just above the rib.[4] Once air returns, the needle is removed while the catheter is left in the chest.[5]

Successful placement will often result in a rush of air and improved vital signs.[6] A chest X-ray is than carried out to verify improvement.[5] Complications may include bleeding, infection, and heart, lung, or diaphragm injury.[4][9] If someone did not previously have a pneumothorax, one may develop.[4]

References

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  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 "How To Reduce a Posterior Hip Dislocation - Injuries; Poisoning". Merck Manuals Professional Edition. Archived from the original on 29 September 2021. Retrieved 29 September 2021.
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Masiewicz, Spencer; Mabrouk, Ahmed; Johnson, Dean E. (2022). "Posterior Hip Dislocation". StatPearls. StatPearls Publishing. Archived from the original on 13 February 2022. Retrieved 13 February 2022.
  3. ↑ Gottlieb, Michael (June 2022). "Managing Posterior Hip Dislocations". Annals of Emergency Medicine. 79 (6): 554–559. doi:10.1016/j.annemergmed.2022.01.027. Archived from the original on 19 August 2022. Retrieved 12 August 2022.
  4. ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 "How To Do Needle Thoracostomy - Pulmonary Disorders". Merck Manuals Professional Edition. Archived from the original on 20 June 2022. Retrieved 9 August 2022.
  5. ↑ 5.0 5.1 5.2 5.3 King, Christopher; Henretig, Fred M. (2008). Textbook of Pediatric Emergency Procedures. Lippincott Williams & Wilkins. p. 355, 365. ISBN 978-0-7817-5386-9. Archived from the original on 2022-08-10. Retrieved 2022-08-09.
  6. ↑ 6.0 6.1 Nagelhout, John J.; Plaus, Karen (11 February 2009). Nurse Anesthesia E-Book. Elsevier Health Sciences. p. 976. ISBN 978-0-323-08101-6. Archived from the original on 10 August 2022. Retrieved 9 August 2022.
  7. ↑ "Needle Thoracentesis". fpnotebook.com. Archived from the original on 15 December 2021. Retrieved 9 August 2022.
  8. ↑ Laan, DV; Vu, TD; Thiels, CA; Pandian, TK; Schiller, HJ; Murad, MH; Aho, JM (April 2016). "Chest wall thickness and decompression failure: A systematic review and meta-analysis comparing anatomic locations in needle thoracostomy". Injury. 47 (4): 797–804. doi:10.1016/j.injury.2015.11.045. PMID 26724173.
  9. ↑ Wernick, Brian; Hon, HeidiH; Mubang, RonnieN; Cipriano, Anthony; Hughes, Ronson; Rankin, DemichaD; Evans, DavidC; Burfeind, WilliamR; Hoey, BrianA; Cipolla, James; Galwankar, SagarC; Papadimos, ThomasJ; Stawicki, StanislawP; Firstenberg, MichaelS (2015). "Complications of needle thoracostomy: A comprehensive clinical review". International Journal of Critical Illness and Injury Science. 5 (3): 160. doi:10.4103/2229-5151.164939.{{cite journal}}: CS1 maint: unflagged free DOI (link)

Category:Mdwiki Translation Dashboard articles


rollback / edit war

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edits

Check out https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death
At one point the article the editor had the cause of death ranking wrong (and uses future predictions insread of past information). This is cited
Those are terrible bulletpoints which could be shortened down a lot. One of the bullet points I edited is the issue, which saw the whole article rolled back.
The "jargon" is used in brackets () with links to other wikipedia pages. This article rollback put information back in the article about the circulation which is wrong. W;ChangingUsername (talk) 18:03, 22 May 2024 (UTC)
Respectfully we're not a medical website, Anywho go to WP:Simple talk as others may disagree with me or may agree and either way will be able to help you better than I can, Thanks, –Davey2010Talk 18:07, 22 May 2024 (UTC)
Added. https://simple.m.wikipedia.org/wiki/Wikipedia:Simple_talk#Stroke_page in case you want to take part in the discussion.
And (reapectfully) the rules say the article needs to be written simply, not that it needs to be less detailed or cover information worse. Roll back your article properly if youre going to try and make it entirely your own

And the FAST memory aid should be remembered by everyone to help spot strokes. W;ChangingUsername (talk) 18:19, 22 May 2024 (UTC)

Never once said it needs to be less detailed or cover worse information, I'm simply saying your edits aren't an improvement over what is there. Thanks. –Davey2010Talk 18:23, 22 May 2024 (UTC)

Rockefeller family

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Tens of thousands of characters deleted (changes page revision link) archived[1] with (web).archive.org.

  1. ↑ "Rockefeller family: Difference between revisions - Simple English Wikipedia, the free encyclopedia". web.archive.org. 2025-04-25. Retrieved 2025-04-25.

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{{Category:Medical education}}

(and before you say - it was working without the duplicate entry, then I added small=no.) {{translated page|simple| yeah...




|User:Catcus_DeMeowwy <!-Scroll to see talk page ->}}
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